New hope for hunter syndrome: Long-Term drug trial launches
NCT ID NCT06075537
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at the long-term safety and effects of an experimental drug called DNL310 for people with Hunter syndrome (MPS II), a rare genetic disorder. About 99 participants who completed earlier studies will receive the drug for up to 5 years. Researchers will monitor side effects and measure changes in disease markers and development.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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ASST di Cremona
Cremona, Italy
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Ann and Robert H Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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Azienda Sanitaria Universitaria Friuli Centrale - PO Universitario Santa Maria della Misericordia
Udine, Italy
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Birmingham Women's and Children's NHS Foundation Trust
Birmingham, United Kingdom
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Drottning Silvias Barn Och Ungdomssjukhus
Gothenburg, Sweden
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Erasmus Medical Center - Sophia Children's Hospital
Rotterdam, 3015 GD, Netherlands
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Gazi Universitesi Tip Fakultes
Ankara, Turkey (Türkiye)
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Great Ormond Street Hospital
London, WC1N 3JH, United Kingdom
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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Hopital Jeanne De Flandre - Metabolic Diseases Unit
Lille, France
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Hospit U. Vall d'Hebron - PPDS
Barcelona, Spain
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Hospital for Sick Children
Toronto, Ontario, M5G 1X8, Canada
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Huntsman Cancer Hospital
Salt Lake City, Utah, 84112, United States
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McGill University Health Center
Montreal, Quebec, H4A3J1, Canada
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Royal Free Hospital
London, NW3 2QG, United Kingdom
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Royal Manchester Children's Hospital
Manchester, United Kingdom
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Sanatorio Mater Dei
Buenos Aires, Argentina
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SpinCS GmbH
Höchheim, Germany
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The University of Texas Medical School at Houston
Houston, Texas, 77030, United States
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UCSF Benioff Children's Hospital Oakland
Oakland, California, 94609, United States
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UNC Children's Research Institute
Chapel Hill, North Carolina, 27599, United States
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UZ Brussel
Jette, Belgium
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Universitair Ziekenhuis Antwerpen
Edegem, Antwerpen, 2650, Belgium
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University Medical Faculty Balcali Hospital
Adana, Turkey (Türkiye)
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University of Alberta - Faculty of Medicine & Dentistry
Edmonton, Alberta, Canada
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Universitätsklinikum Hamburg-Eppendorf
Hamburg, Germany
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Vseobecna Fakultni Nemocnice V Praze
Prague, 120 00, Czechia