Extended treatment tested for lingering COVID heart condition

NCT ID NCT05918978

Summary

This extension study followed adults with post-COVID POTS (a condition causing fast heart rate and dizziness upon standing) who had completed a previous 24-week trial. All 33 participants received the investigational drug efgartigimod via IV to evaluate its long-term safety and whether it continued to help control symptoms like fatigue, brain fog, and orthostatic intolerance over an additional 48 weeks. The study was terminated early, and results focus on safety and patient-reported symptom changes.

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Contacts and locations

Locations

  • Apex Trials Group

    Fort Worth, Texas, 76104, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21205, United States

  • Metrodora Institute

    West Valley City, Utah, 84119, United States

  • North Shore University HealthSystem

    Glenview, Illinois, 60026, United States

  • Pioneer Clinical Research

    Rosharon, Texas, 77583, United States

  • Standford Movement Disorder Center

    Palo Alto, California, 94304, United States

  • UC Sand Diego Sulpizio Cardiovascular Center

    La Jolla, California, 92037, United States

  • University Hospitals, Neurology Clinical Trials

    Cleveland, Ohio, 44106, United States

Conditions

Explore the condition pages connected to this study.