Promising sickle cell drug mitapivat tested for Long-Term safety

NCT ID NCT04610866

First seen Jan 10, 2026 · Last updated May 14, 2026 · Updated 13 times

Summary

This study looks at the long-term safety and tolerability of the drug mitapivat in adults with stable sickle cell disease. Participants, who must have benefited from mitapivat in a prior study, will take the drug twice daily for up to 48 weeks, with an option to continue for another 48 weeks. The study monitors side effects, blood counts, heart and lung function, and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.