Trial tests Long-Term safety of promising liver disease drug duo

NCT ID NCT06488911

Terminated Disease control Sponsor: Intercept Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study aimed to check the long-term safety and side effects of a fixed-dose pill combining two drugs, obeticholic acid and bezafibrate, for people with primary biliary cholangitis (PBC), a chronic liver disease. It was an open-label extension study for 63 participants who had already been in related earlier trials. The main goal was to monitor for any health problems or serious side events over a longer period, while also checking if the treatment helped reduce severe itching and serious liver complications.

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Contacts and locations

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Locations

Academisch Medisch Centrum

Amsterdam, 1005 AZ, Netherlands
Akershus University Hospital

Lørenskog, 1478, Norway
American Research Corporation

San Antonio, Texas, 78215, United States
Artroscan s.r.o. Gastroenterologicka

Ostrava, 722100, Czechia
Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi

Bologna, Italy
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
CHRU de Lille

Lille, 59000, France
CHU Paris Est - Hopital Saint Antoine

Paris, 75012, France
Consorcio Hospital General Universitario

Valencia, 46014, Spain
DEOEC II. sz. Belgygyszati Klinika

Debrecen, 4032, Hungary
DIM Clinica Privada

Buenos Aires, Argentina
East Tennessee Research Institute

Johnson City, Tennessee, 37604, United States
Ege University, Faculty of Medicine, Gastroenterology

Bornova, Turkey (Türkiye)
Flinders Medical Centre

Bedford Park, 5042, Australia
Gastro One

Germantown, Tennessee, 38138, United States
Hacettepe University, Faculty of Medicine, Adult Hospital Gastroenterology

Ankara, Turkey (Türkiye)
Hadassah Ein-Karem Medical Center - Liver unit

Jerusalem, 9112001, Israel
Harran University Hospital, Gastroenterology

Sanliurfa, Turkey (Türkiye)
Hepato-Gastroenterologie HK, s.r.o.

Hradec Králové, 50012, Czechia
Hopital Henri Mondor

Créteil, 94000, France
Hopital de la Pitie Salpetriere

Paris, 75013, France
Hospital ClinicUniversity of Barcelona

Barcelona, 8036, Spain
Hospital Italiano de Buenos Aires

Buenos Aires, Argentina
Hospital Italiano de La Plata

Buenos Aires, Argentina
Hospital Provincial del Centenario

Santa Fe, Argentina
Hospital Universitario Austral

Buenos Aires, Argentina
Houston Methodist Hospital

Houston, Texas, 77030, United States
Hull University Teaching Hospitals NHS Trust

Hull, HU32JZ, United Kingdom
Institute of Cellular Medicine Newcastle University

Newcastle upon Tyne, NE7 7DN, United Kingdom
Istanbul University, Capa Faculty of Medicine, Gastroenterology

Istanbul, Turkey (Türkiye)
John Radcliffe Hospital

Oxford, OX3 9DU, United Kingdom
Kyungpook National University Hospital

Daegu, 41944, South Korea
Medizinische Hochschule Hannover

Hanover, 30625, Germany
NYU Langone Health

New York, New York, 10016, United States
Ochsner Clinic Foundation

New Orleans, Louisiana, 70121, United States
Pacific Gastroenterology Associates GI Research Institute

Vancouver, British Columbia, Canada
Piedmont Atlanta Hospital

Atlanta, Georgia, 30309, United States
Research Site SRO

Pilsen, 30100, Czechia
Royal Adelaide Hospital

Adelaide, 5000, Australia
Seoul National University Bundang Hospital

Seongnam-si, 463-707, South Korea
Southern California Research Center

Coronado, California, 92118, United States
Tampa General Medical Group

Tampa, Florida, 33606, United States
Tartu University Hospital

Tartu, 50090, Estonia
The Liver Institute at Methodist Dallas Medical Center

Dallas, Texas, 75203, United States
UZ Leuven

Leuven, 3000, Belgium
University Hopital Santaros klinikos

Vilnius, 8661, Lithuania
University Hospital of Larissa

Larissa, 41110, Greece
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35233, United States
University of Alberta Division of Gastroenterology Zeidler Ledcor Centre

Edmonton, Alberta, Canada
Universityl Hospital Dubrava

Zagreb, 10 000, Croatia

Conditions

Explore the condition pages connected to this study.

PRIMARY BILIARY CHOLANGITIS