New hope for Hard-to-Transplant patients: Long-Term study tracks kidney survival

NCT ID NCT05714514

First seen Nov 18, 2025 · Last updated Jun 11, 2026 · Updated 24 times

Summary

This study follows 64 highly sensitized patients who received either the drug imlifidase or standard care to help them get a kidney transplant. Researchers want to see how many patients are alive and free from dialysis 3 and 5 years later. The goal is to understand if this desensitization approach leads to lasting transplant success.

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Contacts and locations

Locations

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Columbia University

    New York, New York, 10032, United States

  • Cooperman Barnabas Medical Center

    Livingston, New Jersey, 07039, United States

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • John Hopkins Hospital

    Baltimore, Maryland, 21287, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Methodist Hospital Specialty and Transplant

    San Antonio, Texas, 78229, United States

  • New York University (NYU) Langone Transplant Institute, NYU Langone Health

    New York, New York, 10016, United States

  • Northwestern University, Dept. General Surgery, Div. Transplantation

    Chicago, Illinois, 60611, United States

  • University of Alabama at Birmingham (UAB) Hospital

    Birmingham, Alabama, 35249, United States

  • University of Chicago, Department of Surgery, Clinical Research Center

    Chicago, Illinois, 60637, United States

  • University of Washington Medical Center

    Seattle, Washington, 98195, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.