Major trial tests Long-Term safety of promising skin disease drug

NCT ID NCT06212999

Ongoing Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

Summary

This study follows 617 people with moderate to severe hidradenitis suppurativa (HS), a painful skin condition, to check the long-term safety and effectiveness of the drug povorcitinib. Participants have already completed 54 weeks of treatment in previous studies and will continue taking the medication or a placebo. The main goal is to monitor side effects and see how well the drug continues to control painful lumps and tunnels under the skin over a longer period.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Investigative Site AT305

Vienna, 01090, Austria
Investigative Site AT306

Inssbruck, 06020, Austria
Investigative Site AU200

Liverpool, New South Wales, 02170, Australia
Investigative Site AU201

Carlton, Victoria, 03053, Australia
Investigative Site AU203

Charlestown, New South Wales, 02290, Australia
Investigative Site AU204

Melbourne, Victoria, 03002, Australia
Investigative Site AU205

Kogarah, New South Wales, 02217, Australia
Investigative Site AU206

Woolloongabba, Queensland, 04102, Australia
Investigative Site AU207

Woolloongabba, Queensland, 04102, Australia
Investigative Site BE300

Brussels, 01070, Belgium
Investigative Site BE301

Ghent, 09000, Belgium
Investigative Site BE302

Liège, 04000, Belgium
Investigative Site BG200

Sofia, 01510, Bulgaria
Investigative Site BG201

Stara Zagora, 06000, Bulgaria
Investigative Site BG202

Sofia, 01463, Bulgaria
Investigative Site BG203

Sofia, 01407, Bulgaria
Investigative Site BG204

Sofia, 01606, Bulgaria
Investigative Site CA200

Surrey, British Columbia, V3V 0C6, Canada
Investigative Site CA202

Calgary, Alberta, T3E 0B2, Canada
Investigative Site CA203

St. John's, A1A 4Y3, Canada
Investigative Site CA204

Edmonton, Alberta, T6G 1C3, Canada
Investigative Site CA205

Fredericton, New Brunswick, E3B 1G9, Canada
Investigative Site CA206

Saint-Jérôme, Quebec, J7Z 7E2, Canada
Investigative Site CA207

Mississauga, Ontario, L4W 0C2, Canada
Investigative Site CA208

Richmond Hill, Ontario, L4B 1L1, Canada
Investigative Site CA301

Winnipeg, Manitoba, R3M 3Z4, Canada
Investigative Site CA302

Peterborough, Ontario, K9J 5K2, Canada
Investigative Site CA303

London, Ontario, N6H 5L5, Canada
Investigative Site CA304

Barrie, Ontario, L4M 7G1, Canada
Investigative Site CA307

Montreal, Quebec, H2X 2V1, Canada
Investigative Site CA308

Hamilton, Ontario, L8L 3C3, Canada
Investigative Site CZ300

Prague, 150 06, Czechia
Investigative Site CZ301

Ostrava - Poruba, 708 52, Czechia
Investigative Site DE200

Kiel, 24105, Germany
Investigative Site DE201

Dessau, 06847, Germany
Investigative Site DE202

Berlin, 10117, Germany
Investigative Site DE203

Bochum, 44791, Germany
Investigative Site DE205

Heidelberg, 69120, Germany
Investigative Site DE206

Merzig, 66663, Germany
Investigative Site DE207

Erlangen, 91054, Germany
Investigative Site DE208

Göttingen, 37075, Germany
Investigative Site DE300

Hanover, 30159, Germany
Investigative Site DE301

Frankfurt, 60590, Germany
Investigative Site DE302

Dresden, 01307, Germany
Investigative Site DE303

Hamburg, 20246, Germany
Investigative Site DE305

Darmstadt, 64283, Germany
Investigative Site DE306

Düsseldorf, 40225, Germany
Investigative Site DE307

Memmingen, 87700, Germany
Investigative Site DK200

Århus N, 08200, Denmark
Investigative Site DK201

Roskilde, 04000, Denmark
Investigative Site ES200

Manises, 46940, Spain
Investigative Site ES201

Madrid, 28009, Spain
Investigative Site ES202

Las Palmas de Gran Canaria, 35010, Spain
Investigative Site ES203

Alicante, 03010, Spain
Investigative Site ES205

Madrid, 28040, Spain
Investigative Site ES300

Pontevedra, 36001, Spain
Investigative Site ES301

Granada, 18014, Spain
Investigative Site ES302

Badalona, 08916, Spain
Investigative Site ES303

Barcelona, 08003, Spain
Investigative Site ES304

Santiago de Compostela, 15706, Spain
Investigative Site ES305

Madrid, 28041, Spain
Investigative Site FR202

Rouen, 76031, France
Investigative Site FR203

Nice, 06200, France
Investigative Site FR204

Lyon, 69437, France
Investigative Site FR205

Dijon, 21000, France
Investigative Site FR206

Reims, 51100, France
Investigative Site FR300

Paris, 75010, France
Investigative Site FR301

Saint-Priest-en-Jarez, 42270, France
Investigative Site FR302

Nantes, 44093, France
Investigative Site FR303

Brest, 29609, France
Investigative Site FR304

Marseille, 13385, France
Investigative Site FR305

Bordeaux, 33000, France
Investigative Site FR306

Toulouse, 31059, France
Investigative Site FR307

Le Mans, 72037, France
Investigative Site GB200

Dudley, DY1 2HQ, United Kingdom
Investigative Site GB202

Birmingham, B15 2TH, United Kingdom
Investigative Site GB203

Salford, M6 8HD, United Kingdom
Investigative Site GR300

Athens, 12462, Greece
Investigative Site GR302

Thessaloniki, 56403, Greece
Investigative Site GR303

Athens, 16121, Greece
Investigative Site IT200

Ancona, 60126, Italy
Investigative Site IT201

Rozzano, 20089, Italy
Investigative Site IT202

Milan, 20122, Italy
Investigative Site IT205

Roma, 00136, Italy
Investigative Site IT206

Pisa, 56126, Italy
Investigative Site IT207

Catania, 95123, Italy
Investigative Site JP300

Kyoto, 602-8566, Japan
Investigative Site JP301

Ginowan-shi, 901-2725, Japan
Investigative Site JP302

Sendai, 980-8574, Japan
Investigative Site JP303

Niigata, 951-8520, Japan
Investigative Site JP304

Itabashi-ku, 173-8610, Japan
Investigative Site JP305

Kurume-shi, 830-0011, Japan
Investigative Site JP308

Sapporo, 060-8648, Japan
Investigative Site JP309

Shinjuku-ku, 160-0023, Japan
Investigative Site NL301

Rotterdam, 3015 GD, Netherlands
Investigative Site NL302

Breda, 4818 CK, Netherlands
Investigative Site NL303

Groningen, 9713 GZ, Netherlands
Investigative Site PL200

Rzeszów, 35-055, Poland
Investigative Site PL201

Warsaw, 02-507, Poland
Investigative Site PL202

Warsaw, 02-962, Poland
Investigative Site PL203

Lublin, 20573, Poland
Investigative Site PL301

Wroclaw, 50-566, Poland
Investigative Site PL302

Wroclaw, 51-503, Poland
Investigative Site PL304

Ostrowiec Świętokrzyski, 27-400, Poland
Investigative Site US200

Ocala, Florida, 34470, United States
Investigative Site US201

Tampa, Florida, 33613, United States
Investigative Site US202

New York, New York, 10028, United States
Investigative Site US203

Gahanna, Ohio, 43230, United States
Investigative Site US204

Miami, Florida, 33125, United States
Investigative Site US205

Chapel Hill, North Carolina, 27516, United States
Investigative Site US206

Indianapolis, Indiana, 46250, United States
Investigative Site US207

Metairie, Louisiana, 70006, United States
Investigative Site US209

Louisville, Kentucky, 40241, United States
Investigative Site US210

Rochester, New York, 14620, United States
Investigative Site US212

Minneapolis, Minnesota, 55455, United States
Investigative Site US213

Fort Gratiot, Michigan, 48059, United States
Investigative Site US214

Rogers, Arkansas, 72758, United States
Investigative Site US215

Bexley, Ohio, 43209, United States
Investigative Site US217

Waterford, Michigan, 48328, United States
Investigative Site US218

Bellaire, Texas, 77401, United States
Investigative Site US220

West Dundee, Illinois, 60118, United States
Investigative Site US221

Quincy, Massachusetts, 02169, United States
Investigative Site US222

Oakland, California, 94611, United States
Investigative Site US223

Los Angeles, California, 90033, United States
Investigative Site US224

Baltimore, Maryland, 21287, United States
Investigative Site US225

Boston, Massachusetts, 02115, United States
Investigative Site US226

San Diego, California, 92103, United States
Investigative Site US227

Margate, Florida, 33063, United States
Investigative Site US228

Tampa, Florida, 33609, United States
Investigative Site US229

New Orleans, Louisiana, 70115, United States
Investigative Site US230

East Windsor, New Jersey, 08520, United States
Investigative Site US232

Murfreesboro, Tennessee, 37130, United States
Investigative Site US234

San Antonio, Texas, 78213, United States
Investigative Site US235

Arlington, Texas, 76011, United States
Investigative Site US236

Miami, Florida, 33173, United States
Investigative Site US238

Pflugerville, Texas, 78660, United States
Investigative Site US240

Scottsdale, Arizona, 85255, United States
Investigative Site US300

Plano, Texas, 75025, United States
Investigative Site US301

Portland, Oregon, 97201, United States
Investigative Site US302

St Louis, Missouri, 63110, United States
Investigative Site US303

Phoenix, Arizona, 85006, United States
Investigative Site US304

Boston, Massachusetts, 02215, United States
Investigative Site US305

Baton Rouge, Louisiana, 70809, United States
Investigative Site US306

Hollywood, Florida, 33021, United States
Investigative Site US307

Fort Smith, Arkansas, 72916, United States
Investigative Site US308

Spokane, Washington, 99202, United States
Investigative Site US309

Clearwater, Florida, 33614, United States
Investigative Site US310

Brighton, Massachusetts, 02135, United States
Investigative Site US311

Marietta, Georgia, 30060, United States
Investigative Site US312

Cleveland, Ohio, 44106, United States
Investigative Site US313

Norfolk, Virginia, 23502, United States
Investigative Site US314

Cincinnati, Ohio, 45219, United States
Investigative Site US315

Laguna Niguel, California, 92677, United States
Investigative Site US316

Maitland, Florida, 32751, United States
Investigative Site US317

Hialeah, Florida, 33012-3618, United States
Investigative Site US318

Portsmouth, New Hampshire, 03801, United States
Investigative Site US320

Hollywood, Florida, 33021, United States
Investigative Site US321

North Miami Beach, Florida, 33162-4708, United States
Investigative Site US324

Kew Gardens, New York, 11415, United States
Investigative Site US325

Marriottsville, Maryland, 21104, United States
Investigative Site US330

Boardman, Ohio, 44512, United States
Investigative Site US337

Indianapolis, Indiana, 46250, United States
Investigative Site US339

Bexley, Ohio, 43209, United States
Investigative Site US340

Bellaire, Texas, 77401, United States
Investigative Site US341

Bowling Green, Kentucky, 42104, United States

Conditions

Explore the condition pages connected to this study.

HIDRADENITIS SUPPURATIVA (HS)