Five-Year trial tests drug for severe skin disease flares

NCT ID NCT03886246

Summary

This study is testing the long-term safety and effectiveness of the drug spesolimab for people with generalized pustular psoriasis (GPP), a serious skin condition. Participants who previously took spesolimab in earlier trials receive the drug for nearly five years to see how well it controls their symptoms and prevents painful flare-ups. Doctors monitor participants' skin and overall health throughout the study to understand the drug's long-term benefits and risks.

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Contacts and locations

Locations

  • Center for Skin Research, Testing and Product Development

    Makati City, 1229, Philippines

  • Chang Gung Medical Foundation (CGMF) - Linkou Bran

    Linkou District, 333, Taiwan

  • Charité - Universitätsmedizin Berlin

    Berlin, 10117, Germany

  • Cliniques Universitaires Saint-Luc

    Brussels, 1200, Belgium

  • Clínica Dermacross S.A.

    Vitacura, 7640881, Chile

  • FSBEI HE "Kirov State Medical University"

    Kirov, 610035, Russia

  • Fachklinik Bad Bentheim

    Bad Bentheim, 48455, Germany

  • Farhat Hached Hospital

    Sousse, 4000, Tunisia

  • HCMC Hospital of Dermato-Venereology-Ho Chi Minh-66092

    Ho Chi Minh City, 70000, Vietnam

  • HOP Robert Debré

    Reims, 51092, France

  • HOP Saint-André

    Bordeaux, 33000, France

  • HOP Saint-Louis

    Paris, 75010, France

  • Hedi Chaker Hospital, Department of Dermatology

    Tunisia, 1053, Tunisia

  • Hospital Italiano de Buenos Aires

    CABA, C1199ABD, Argentina

  • Hospital Kuala Lumpur

    Kuala Lumpur, 50586, Malaysia

  • Hospital Pakar Sultanah Fatimah

    Muar town, 84000, Malaysia

  • Hospital Pulau Pinang-Pulau Pinang-21953

    George Town, 10990, Malaysia

  • Hospital Raja Permaisuri Bainun

    Ipoh, 30450, Malaysia

  • Hospital Sant Joan de Déu

    Esplugues Del Llobregat, 08950, Spain

  • Hospital Selayang

    Kuala Selangor, 68100, Malaysia

  • Hospital Sultan Ismail

    Johor Bahru, 81100, Malaysia

  • Hospital Sultanah Aminah

    Johor Bahru, 80100, Malaysia

  • Hospital Universitario Dr Jose Eleuterio Gonzalez

    Monterrey, 64460, Mexico

  • Huashan Hospital, Fudan University

    Shanghai, 200040, China

  • Hôpital de l'Archet

    Nice, 06200, France

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Iloilo Doctors Hospital

    Iloilo City, Iloilo, 5000, Philippines

  • Institute of Dermatology

    Bangkok, 10400, Thailand

  • Istituto Clinico Humanitas

    Rozzano (MI), 20089, Italy

  • Klinikum Oldenburg AöR

    Oldenburg, 26133, Germany

  • Klinikum der Universität München - Campus Innenstadt

    München, 80337, Germany

  • LLC "Medical Center Azbuka Zdorovia"

    Kazan', 420111, Russia

  • LLC Skin Disease Clinic of Pier Volkenstein, St. Petersburg

    Saint Petersburg, 190123, Russia

  • La Rabta Hospital

    Tunis, 1007, Tunisia

  • Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi

    Istanbul, 34890, Turkey (Türkiye)

  • Nagoya City University Hospital

    Aichi, Nagoya, 467-8602, Japan

  • National Hospital of Dermatology and Venereology

    Hà Nội, 10000, Vietnam

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Oakland Hills Dermatology

    Auburn Hills, Michigan, 48326, United States

  • Queen Elizabeth Hospital

    Kota Kinabalu, 88586, Malaysia

  • Ramathibodi Hospital

    Bangkok, 10400, Thailand

  • SBHI Chelyabinsk Reg.Clin.Derma.Dispen.

    Chelyabinsk, 454048, Russia

  • Saitama Medical University Hospital

    Saitama, Iruma-gun, 350-0495, Japan

  • Saratov State Med.Univ.n.a.Razumovskogo

    Saratov, 410028, Russia

  • Sarawak General Hospital

    Kuching, Sarawak, 93586, Malaysia

  • Second Affiliated Hospital of Xi'an JiaoTong University

    Xi'an, 710004, China

  • Severance Hospital

    Seoul, 03722, South Korea

  • Shanghai Skin Disease Hospital

    Shanghai, 200000, China

  • Singapore General Hospital

    Singapore, 169608, Singapore

  • Southern Philippines Medical Center -Davao-62091

    Davao City, 8000, Philippines

  • Sun yet-sen Memorial Hospital, Sun yet-sen Univesity

    Guangzhou, 510288, China

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    Hangzhou, 310009, China

  • Tokyo Medical University Hachioji Medical Center

    Tokyo, Hachioji, 193-0998, Japan

  • Tokyo Medical University Ibaraki Medical Center

    Ibaraki, Inashiki-gun, 300-0395, Japan

  • Universitätsklinikum Bonn AöR

    Bonn, 53127, Germany

  • Universitätsklinikum Frankfurt

    Frankfurt am Main, 60596, Germany

  • Westfälische Wilhelms-Universität Münster

    Münster, 48149, Germany

Conditions

Explore the condition pages connected to this study.