Gene-edited cell therapy for sickle cell disease: what happens years later?

NCT ID NCT06155500

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 32 times

Summary

This study follows 4 people with sickle cell disease who already received a gene-edited cell therapy called OTQ923. Researchers will check for delayed side effects, such as new cancers or blood disorders, and measure how long the therapy's benefits last. The goal is to understand the long-term safety and effectiveness of this one-time treatment.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Ctr

    New York, New York, 10065, United States

  • St Jude Childrens Research Hospital

    Memphis, Tennessee, 38105, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.