Extended treatment trial offers hope for managing rare genetic disorder

NCT ID NCT03614234

Summary

This study continues testing an enzyme replacement therapy called pegunigalsidase alfa in adults with Fabry disease who finished a previous trial. Researchers want to understand the long-term safety and effectiveness of receiving this medication through an IV every four weeks. They will monitor kidney and heart function, pain levels, and overall quality of life over an extended period.

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Contacts and locations

Locations

  • Addenbrooke's Hospital

    Cambridge, CB2 0QQ, United Kingdom

  • Azienda Ospedaliera Universitaria "Federico II"

    Naples, Via Pansini, 80131, Italy

  • Emory University School of Medicine

    Atlanta, Georgia, 30307, United States

  • Fakultní poliklinika Všeobecné fakultní nemocnice v Praze

    Prague, 128 08, Czechia

  • Helse Bergen HF Haukeland Universitetssykehus

    Bergen, 5021, Norway

  • Infusion Associates

    Grand Rapids, Michigan, 49525, United States

  • Medical Endocrinology PE 2132, Rigshospitalet

    Copenhagen, 2100, Denmark

  • O & O Alpan

    Fairfax, Virginia, 22030, United States

  • Renal Disease Research Institute, LLC

    Dallas, Texas, 75235, United States

  • The Royal Free Hospital

    London, United Kingdom

  • UAB Medicine

    Birmingham, Alabama, 35233, United States

  • UZ Antwerpen

    Edegem, 2650, Belgium

  • University of Iowa Hospitals and Clinica

    Iowa City, Iowa, 52242, United States

  • University of Utah Hospitals & Clinics

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.