Three-Year eye injection study aims to halt blinding disease

NCT ID NCT04770545

Summary

This study followed people for up to three years to see if regular injections of the drug pegcetacoplan into the eye are safe and can continue to slow the progression of geographic atrophy, a form of advanced age-related macular degeneration that causes permanent vision loss. It included 792 people who had already completed earlier trials of the same drug. Researchers measured the size of the eye damage and checked vision over time to see if the treatment remained effective.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AIO Visionary Eye Care

    West Mifflin, Pennsylvania, 15122, United States

  • ASST Fatebenefratelli-Sacco Ospedale Luigi Sacco

    Milan, 20157, Italy

  • AXON Clinical, s.r.o.

    Prague, 150 00, Czechia

  • Academisch Medisch Centrum

    Amsterdam, 1105 AZ, Netherlands

  • Assaf ha Rofeh MC

    Be’er Ya‘aqov, 7030000, Israel

  • Associated Retina Consultants, Ltd.

    Phoenix, Arizona, 85020, United States

  • Associated Retinal Consultants, PC

    Grand Rapids, Michigan, 49546, United States

  • Associated Retinal Consultants, PC

    Traverse City, Michigan, 49686, United States

  • Atlantis Eyecare

    Huntington Beach, California, 92647, United States

  • Augenklinik der LMU Munchen

    München, 80336, Germany

  • Augenzentrum am St. Franziskus-Hospital

    Münster, 48145, Germany

  • Bascom Palmer Eye Institute

    Miami, Florida, 33136, United States

  • Bascom Palmer Eye Institute at Naples

    Naples, Florida, 34103, United States

  • Bay Area Retina Associates

    Walnut Creek, California, 94598, United States

  • Black Hills Regional Eye Institute

    Rapid City, South Dakota, 57701, United States

  • Blue Ocean Clinical Research

    Clearwater, Florida, 33761, United States

  • Bristol Eye Hospital

    Bristol, BS1 2LX, United Kingdom

  • Brown Retina Institute

    Bellaire, Texas, 77401, United States

  • Byers Eye Institute, Stanford University

    Palo Alto, California, 94303, United States

  • CHNO des Quinze-Vingts

    Paris, 75012, France

  • CHU Dijon

    Dijon, 21 079, France

  • CHU de Bordeaux

    Bordeaux, 33076, France

  • CHU de Nantes - Hotel Dieu

    Nantes, 44093, France

  • CHU de Strasbourg Hopital Civil

    Strasbourg, 67091, France

  • California Retina Consultants

    Bakersfield, California, 93309, United States

  • California Retina Consultants

    Santa Barbara, California, 93103, United States

  • Center for Retina and Macular Disease

    Winter Haven, Florida, 33880, United States

  • Centre Hospitalier Intercommunal de Creteil

    Créteil, 94010, France

  • Centre Ophtalmo. Image/Laser

    Paris, 75015, France

  • Centre Ophtalmol de l Odeon

    Paris, 75006, France

  • Centre for Eye Research Australia

    East Melbourne, Victoria, 3002, Australia

  • Centre monticelli Paradis

    Marseille, 13008, France

  • Centre ophtalmologique Saint-Exupery

    Saint-Cyr-sur-Loire, Lyon, 37540, France

  • Centro Oftalmologico Dr. Charles S.A.

    Buenos Aires, C1116ABA, Argentina

  • Charles Retina Institute

    Germantown, Tennessee, 38138, United States

  • Charlotte Eye Ear Nose and Throat Associates, PS

    Charlotte, North Carolina, 28210, United States

  • Cleveland Clinic Cole Eye Institute

    Cleveland, Ohio, 44195, United States

  • Clinique du Val d'Ouest

    Écully, 69130, France

  • Cumberland Valley Retina Center

    Hagerstown, Maryland, 21740, United States

  • Danbury Eye Physicians & Surgeons, PC

    Danbury, Connecticut, 06810, United States

  • Diagnostico Ocular

    Buenos Aires, 1425, Argentina

  • Doheny Eye Center UCLA

    Los Angeles, California, 90033, United States

  • Duke University, Duke Eye Center

    Durham, North Carolina, 27710, United States

  • East Florida Eye Institute

    Stuart, Florida, 34994, United States

  • Elman Retina Group

    Baltimore, Maryland, 21236, United States

  • Emerson Clinical Research Institute

    Falls Church, Virginia, 22046, United States

  • Eye Associates of Pinellas

    Pinellas Park, Florida, 33782, United States

  • Eye Health Northwest

    Portland, Oregon, 97225, United States

  • Eye Surgery Center Professor Zagorski

    Bydgoszcz, 85-316, Poland

  • Fakultni Nemocnice Ostrava

    Ostrava-Poruba, 708 52, Czechia

  • Florida Eye Microsurgical Institute, Inc.

    Boynton Beach, Florida, 33426, United States

  • Fundacion Zambrano

    Buenos Aires, C1023 AAQ, Argentina

  • Gailey Eye Clinic Retina Center

    Bloomington, Illinois, 61704, United States

  • Gemini Eye Clinic

    Zlín, 760 01, Czechia

  • Georgia Retina, PC

    Marietta, Georgia, 30060, United States

  • Graystone Eye

    Hickory, North Carolina, 28602, United States

  • Grupo Laser Vision

    Rzeszów, 35-017, Poland

  • Hadassah Medical Center

    Jerusalem, 91120, Israel

  • Hamilton Eye Clinic

    Hamilton, 3204, New Zealand

  • Hopital Lariboisiere

    Paris, 75010, France

  • Hopital de la Croix-Rousse

    Lyon, 69004, France

  • Hospital Universitario Puerta de Hierro

    Madrid, 28222, Spain

  • Houston Eye Associates

    Houston, Texas, 77025, United States

  • Huddersfield Royal Infirmary

    Huddersfield, West Yorkshire, HD3 3EA, United Kingdom

  • IPEPO Instituto Da Visao

    São Paulo, 04038-032, Brazil

  • IRCCS San Raffaele

    Milan, 20132, Italy

  • Instituto Oftalmologico Gomez-Ulla

    Santiago de Compostela, 15706, Spain

  • Instituto Oftalmologico de Cordoba

    Córdoba, 5000, Argentina

  • Ivey Eye Institute

    London, Ontario, N6A 4V2, Canada

  • Jacobs Retina Center, UCSD

    La Jolla, California, 92093, United States

  • Kings College Hospital NHS Trust

    London, London, SE5 9RS, United Kingdom

  • Klinikum der Stadt Ludwigshafen gGmbH

    Ludwigshafen, 67063, Germany

  • Klinikum rechts der Isar

    München, 81675, Germany

  • Lions Eye Institute

    Nedlands, 6009, Australia

  • London Vision Clinic

    London, W1G 7LA, United Kingdom

  • Long Island Vitreoretinal Consultants

    Great Neck, New York, 11021, United States

  • Maison Rouge Ophthalmologic Center

    Strasbourg, 67000, France

  • Marsden Eye Specialist

    Parramatta, New South Wales, 2150, Australia

  • Medical Center Ophthalmology Associates

    San Antonio, Texas, 78240, United States

  • Michigan Medicine Kellogg Eye Center

    Ann Arbor, Michigan, 48105, United States

  • Microcirujia Ocular Rosario

    Rosario, 2000, Argentina

  • Mid Atlantic Retina

    Bethlehem, Pennsylvania, 18107, United States

  • Mid Atlantic Retina

    Philadelphia, Pennsylvania, 19006, United States

  • Mid Atlantic Retina

    Philadelphia, Pennsylvania, 19107, United States

  • Mid Atlantic Retina Specialist

    Hagerstown, Maryland, 21740, United States

  • Midwest Eye Institute

    Indianapolis, Indiana, 46290, United States

  • NJ Retina

    Teaneck, New Jersey, 07666, United States

  • NJ Retina

    Toms River, New Jersey, 08755, United States

  • National Opthalmic Research Institute

    Fort Myers, Florida, 33912, United States

  • New England Retina Consultants, PC

    Springfield, Massachusetts, 01107, United States

  • Northern California Retina Vitreous Associates

    Mountain View, California, 94040, United States

  • Northwestern Feinberg School of Medicine

    Chicago, Illinois, 60611, United States

  • OFTAR

    Mendoza, 5500, Argentina

  • Oculomedica Eye Centre

    Tarnów, 33-100, Poland

  • Oftalmika Eye Hospital

    Bydgoszcz, 85-631, Poland

  • Oftalmologos Especialistas

    Santa Fe, S2000, Argentina

  • Ophthalmic Consultants of Boston

    Boston, Massachusetts, 02114, United States

  • Ophthalmic Consultants of Long Island

    Oceanside, New York, 11572, United States

  • Orange County Retina Medical Group

    Santa Ana, California, 92705, United States

  • Oregon Retina LLP

    Eugene, Oregon, 97405, United States

  • Organizacion Medica de Investigacion (OMI)

    Buenos Aires, C1015 ABO, Argentina

  • Oxford Eye Hospital

    Oxford, OX3 9DU, United Kingdom

  • Palm Beach Gardens

    Palm Beach Gardens, Florida, 33418, United States

  • Pinnacle Research Insitute

    Fort Lauderdale, Florida, 33309, United States

  • Radboud university medical center Oogheelkunde

    Nijmegen, 6525 EX, Netherlands

  • Rambam Health Care Campus

    Haifa, 3109601, Israel

  • Retina Associates of Cleveland

    Cleveland, Ohio, 44130, United States

  • Retina Associates of Cleveland, Inc.

    Cleveland, Ohio, 44122, United States

  • Retina Associates of Cleveland, Inc.

    Youngstown, Ohio, 44505, United States

  • Retina Associates of Florida

    Tampa, Florida, 33609, United States

  • Retina Associates of South Texas

    San Antonio, Texas, 78240, United States

  • Retina Associates of Utah, PC

    Murray, Utah, 84107, United States

  • Retina Center of NJ, LLC

    Bloomfield, New Jersey, 07003, United States

  • Retina Centre of Ottawa

    Ottawa, Ontario, K2B 7E9, Canada

  • Retina Consultants San Diego

    Poway, California, 92064, United States

  • Retina Consultants of Houston

    The Woodlands, Texas, 77384, United States

  • Retina Consultants of Houston, PA

    Houston, Texas, 77030, United States

  • Retina Consultants of Orange County

    Fullerton, California, 92835, United States

  • Retina Group of New England - New London

    Waterford, Connecticut, 06835, United States

  • Retina Health Center

    Fort Myers, Florida, 33907, United States

  • Retina Health Center

    Madison, Wisconsin, 53705, United States

  • Retina Institute of California Medical Group

    Palm Desert, California, 92260, United States

  • Retina Northwest, PC

    Portland, Oregon, 97221, United States

  • Retina Research Center PLLC

    Austin, Texas, 78750, United States

  • Retina Specialty Institute

    Pensacola, Florida, 32503, United States

  • Retina Vitreous Center, PLLC

    Edmond, Oklahoma, 73013, United States

  • Retina Vitreous Consultants

    Monroeville, Pennsylvania, 15146, United States

  • Retina and Eye Consultantss

    Hurstville, 2220, Australia

  • Retina and Vitreous Associates of Kentucky, PSC dba Retina Associates of Kentucky

    Lexington, Kentucky, 40509, United States

  • Retina-Vitreous Associates Medical Group

    Madison, Wisconsin, 53705, United States

  • Retinal Diagnostic Center

    Campbell, California, 95508, United States

  • Retinal Research Institue, LLC

    Phoenix, Arizona, 85014, United States

  • Royal Liverpool University Hospital

    Liverpool, L7 8XP, United Kingdom

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • STZ Eyetrial

    Tübingen, 72076, Germany

  • Save Sight Institute

    Westmead, 2145, Australia

  • Sierra Eye Associates

    Reno, Nevada, 89503, United States

  • Southeast Retina Center, PC

    Augusta, Georgia, 30909, United States

  • Southern Eye Specialists

    Christchurch, 8013, New Zealand

  • Southwest Retina Research Center, LLC

    Durango, Colorado, 81301, United States

  • Spokane Eye Clinical Research

    Spokane, Washington, 99204, United States

  • St James's University Hospital

    Leeds, West Yorkshire, LS9 7TF, United Kingdom

  • Strathfield Retina Clinic

    Strathfield, New South Wales, 2135, Australia

  • Sunderland Eye Infirmary

    Sunderland, SR2 9HP, United Kingdom

  • Sydney Retina

    Sydney, New South Wales, 2000, Australia

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, 64239, Israel

  • Tennessee Retina, PC

    Nashville, Tennessee, 78503, United States

  • Texas Retina Associates

    Dallas, Texas, 75231, United States

  • The Ashley Centre

    Westmead, New South Wales, 2145, Australia

  • The Ohio State University

    Columbus, Ohio, 43212, United States

  • The Retina Care Center

    Baltimore, Maryland, 21209, United States

  • The Retina Group of Washington

    Chevy Chase, Maryland, 92705, United States

  • The Retina Group of Washington

    Fairfax, Virginia, 22031, United States

  • The Retina Partners

    Encino, California, 91436, United States

  • Tufts Medical Center

    Boston, Massachusetts, 02116, United States

  • UNO-MED Centrum Medyne

    Tarnów, 33-100, Poland

  • Uni-medizin Gottingen Augenklinik 3.B1.261

    Göttingen, 37075, Germany

  • Uniklinik Koln

    Cologne, 50937, Germany

  • Universitats-Augenklinik Bonn

    Bonn, 53127, Germany

  • Universitatsklinikum Munster

    Münster, 48149, Germany

  • Universitatsklinikum Regensburg

    Münster, 48145, Germany

  • Universitatsklinikum Schleswig-Holstein

    Lübeck, 23538, Germany

  • University Opthalmology Clinic

    Freiburg im Breisgau, 79106, Germany

  • University hospital Kralovske Vinohrady

    Prague, 10034, Czechia

  • University of Ottawa Eye Institute

    Ottawa, Ontario, K1H 8L6, Canada

  • University of South Florida

    Tampa, Florida, 33612, United States

  • University of Utah - John A. Moran Center

    Salt Lake City, Utah, 84312, United States

  • University of Virginia

    Charlottesville, Virginia, 22903, United States

  • Valley Retina Institute

    McAllen, Texas, 78503, United States

  • Vision Research Center Eye Associates of NM

    Albuquerque, New Mexico, 87109, United States

  • Vitreoretinal Associates of Washington

    Bellevue, Washington, 98004, United States

  • Vitreoretinal Surgery

    Minneapolis, Minnesota, 55435, United States

  • Vitreous Retina Macula Consultants of New York

    New York, New York, 10022, United States

  • Vseobecna fakultni nemocnice v Praze

    Prague, 2128 08, Czechia

  • Western Carolina Retinal Associates

    Asheville, North Carolina, 28803, United States

Conditions

Explore the condition pages connected to this study.