Three-Year eye injection study aims to halt blinding disease
NCT ID NCT04770545
Summary
This study followed people for up to three years to see if regular injections of the drug pegcetacoplan into the eye are safe and can continue to slow the progression of geographic atrophy, a form of advanced age-related macular degeneration that causes permanent vision loss. It included 792 people who had already completed earlier trials of the same drug. Researchers measured the size of the eye damage and checked vision over time to see if the treatment remained effective.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AIO Visionary Eye Care
West Mifflin, Pennsylvania, 15122, United States
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ASST Fatebenefratelli-Sacco Ospedale Luigi Sacco
Milan, 20157, Italy
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AXON Clinical, s.r.o.
Prague, 150 00, Czechia
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Academisch Medisch Centrum
Amsterdam, 1105 AZ, Netherlands
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Assaf ha Rofeh MC
Be’er Ya‘aqov, 7030000, Israel
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Associated Retina Consultants, Ltd.
Phoenix, Arizona, 85020, United States
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Associated Retinal Consultants, PC
Grand Rapids, Michigan, 49546, United States
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Associated Retinal Consultants, PC
Traverse City, Michigan, 49686, United States
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Atlantis Eyecare
Huntington Beach, California, 92647, United States
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Augenklinik der LMU Munchen
München, 80336, Germany
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Augenzentrum am St. Franziskus-Hospital
Münster, 48145, Germany
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Bascom Palmer Eye Institute
Miami, Florida, 33136, United States
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Bascom Palmer Eye Institute at Naples
Naples, Florida, 34103, United States
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Bay Area Retina Associates
Walnut Creek, California, 94598, United States
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Black Hills Regional Eye Institute
Rapid City, South Dakota, 57701, United States
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Blue Ocean Clinical Research
Clearwater, Florida, 33761, United States
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Bristol Eye Hospital
Bristol, BS1 2LX, United Kingdom
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Brown Retina Institute
Bellaire, Texas, 77401, United States
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Byers Eye Institute, Stanford University
Palo Alto, California, 94303, United States
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CHNO des Quinze-Vingts
Paris, 75012, France
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CHU Dijon
Dijon, 21 079, France
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CHU de Bordeaux
Bordeaux, 33076, France
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CHU de Nantes - Hotel Dieu
Nantes, 44093, France
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CHU de Strasbourg Hopital Civil
Strasbourg, 67091, France
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California Retina Consultants
Bakersfield, California, 93309, United States
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California Retina Consultants
Santa Barbara, California, 93103, United States
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Center for Retina and Macular Disease
Winter Haven, Florida, 33880, United States
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Centre Hospitalier Intercommunal de Creteil
Créteil, 94010, France
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Centre Ophtalmo. Image/Laser
Paris, 75015, France
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Centre Ophtalmol de l Odeon
Paris, 75006, France
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Centre for Eye Research Australia
East Melbourne, Victoria, 3002, Australia
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Centre monticelli Paradis
Marseille, 13008, France
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Centre ophtalmologique Saint-Exupery
Saint-Cyr-sur-Loire, Lyon, 37540, France
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Centro Oftalmologico Dr. Charles S.A.
Buenos Aires, C1116ABA, Argentina
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Charles Retina Institute
Germantown, Tennessee, 38138, United States
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Charlotte Eye Ear Nose and Throat Associates, PS
Charlotte, North Carolina, 28210, United States
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Cleveland Clinic Cole Eye Institute
Cleveland, Ohio, 44195, United States
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Clinique du Val d'Ouest
Écully, 69130, France
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Cumberland Valley Retina Center
Hagerstown, Maryland, 21740, United States
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Danbury Eye Physicians & Surgeons, PC
Danbury, Connecticut, 06810, United States
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Diagnostico Ocular
Buenos Aires, 1425, Argentina
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Doheny Eye Center UCLA
Los Angeles, California, 90033, United States
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Duke University, Duke Eye Center
Durham, North Carolina, 27710, United States
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East Florida Eye Institute
Stuart, Florida, 34994, United States
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Elman Retina Group
Baltimore, Maryland, 21236, United States
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Emerson Clinical Research Institute
Falls Church, Virginia, 22046, United States
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Eye Associates of Pinellas
Pinellas Park, Florida, 33782, United States
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Eye Health Northwest
Portland, Oregon, 97225, United States
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Eye Surgery Center Professor Zagorski
Bydgoszcz, 85-316, Poland
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Fakultni Nemocnice Ostrava
Ostrava-Poruba, 708 52, Czechia
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Florida Eye Microsurgical Institute, Inc.
Boynton Beach, Florida, 33426, United States
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Fundacion Zambrano
Buenos Aires, C1023 AAQ, Argentina
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Gailey Eye Clinic Retina Center
Bloomington, Illinois, 61704, United States
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Gemini Eye Clinic
Zlín, 760 01, Czechia
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Georgia Retina, PC
Marietta, Georgia, 30060, United States
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Graystone Eye
Hickory, North Carolina, 28602, United States
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Grupo Laser Vision
Rzeszów, 35-017, Poland
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Hadassah Medical Center
Jerusalem, 91120, Israel
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Hamilton Eye Clinic
Hamilton, 3204, New Zealand
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Hopital Lariboisiere
Paris, 75010, France
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Hopital de la Croix-Rousse
Lyon, 69004, France
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Hospital Universitario Puerta de Hierro
Madrid, 28222, Spain
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Houston Eye Associates
Houston, Texas, 77025, United States
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Huddersfield Royal Infirmary
Huddersfield, West Yorkshire, HD3 3EA, United Kingdom
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IPEPO Instituto Da Visao
São Paulo, 04038-032, Brazil
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IRCCS San Raffaele
Milan, 20132, Italy
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Instituto Oftalmologico Gomez-Ulla
Santiago de Compostela, 15706, Spain
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Instituto Oftalmologico de Cordoba
Córdoba, 5000, Argentina
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Ivey Eye Institute
London, Ontario, N6A 4V2, Canada
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Jacobs Retina Center, UCSD
La Jolla, California, 92093, United States
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Kings College Hospital NHS Trust
London, London, SE5 9RS, United Kingdom
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Klinikum der Stadt Ludwigshafen gGmbH
Ludwigshafen, 67063, Germany
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Klinikum rechts der Isar
München, 81675, Germany
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Lions Eye Institute
Nedlands, 6009, Australia
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London Vision Clinic
London, W1G 7LA, United Kingdom
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Long Island Vitreoretinal Consultants
Great Neck, New York, 11021, United States
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Maison Rouge Ophthalmologic Center
Strasbourg, 67000, France
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Marsden Eye Specialist
Parramatta, New South Wales, 2150, Australia
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Medical Center Ophthalmology Associates
San Antonio, Texas, 78240, United States
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Michigan Medicine Kellogg Eye Center
Ann Arbor, Michigan, 48105, United States
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Microcirujia Ocular Rosario
Rosario, 2000, Argentina
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Mid Atlantic Retina
Bethlehem, Pennsylvania, 18107, United States
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Mid Atlantic Retina
Philadelphia, Pennsylvania, 19006, United States
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Mid Atlantic Retina
Philadelphia, Pennsylvania, 19107, United States
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Mid Atlantic Retina Specialist
Hagerstown, Maryland, 21740, United States
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Midwest Eye Institute
Indianapolis, Indiana, 46290, United States
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NJ Retina
Teaneck, New Jersey, 07666, United States
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NJ Retina
Toms River, New Jersey, 08755, United States
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National Opthalmic Research Institute
Fort Myers, Florida, 33912, United States
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New England Retina Consultants, PC
Springfield, Massachusetts, 01107, United States
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Northern California Retina Vitreous Associates
Mountain View, California, 94040, United States
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Northwestern Feinberg School of Medicine
Chicago, Illinois, 60611, United States
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OFTAR
Mendoza, 5500, Argentina
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Oculomedica Eye Centre
Tarnów, 33-100, Poland
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Oftalmika Eye Hospital
Bydgoszcz, 85-631, Poland
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Oftalmologos Especialistas
Santa Fe, S2000, Argentina
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Ophthalmic Consultants of Boston
Boston, Massachusetts, 02114, United States
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Ophthalmic Consultants of Long Island
Oceanside, New York, 11572, United States
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Orange County Retina Medical Group
Santa Ana, California, 92705, United States
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Oregon Retina LLP
Eugene, Oregon, 97405, United States
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Organizacion Medica de Investigacion (OMI)
Buenos Aires, C1015 ABO, Argentina
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Oxford Eye Hospital
Oxford, OX3 9DU, United Kingdom
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Palm Beach Gardens
Palm Beach Gardens, Florida, 33418, United States
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Pinnacle Research Insitute
Fort Lauderdale, Florida, 33309, United States
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Radboud university medical center Oogheelkunde
Nijmegen, 6525 EX, Netherlands
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Rambam Health Care Campus
Haifa, 3109601, Israel
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Retina Associates of Cleveland
Cleveland, Ohio, 44130, United States
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Retina Associates of Cleveland, Inc.
Cleveland, Ohio, 44122, United States
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Retina Associates of Cleveland, Inc.
Youngstown, Ohio, 44505, United States
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Retina Associates of Florida
Tampa, Florida, 33609, United States
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Retina Associates of South Texas
San Antonio, Texas, 78240, United States
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Retina Associates of Utah, PC
Murray, Utah, 84107, United States
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Retina Center of NJ, LLC
Bloomfield, New Jersey, 07003, United States
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Retina Centre of Ottawa
Ottawa, Ontario, K2B 7E9, Canada
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Retina Consultants San Diego
Poway, California, 92064, United States
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Retina Consultants of Houston
The Woodlands, Texas, 77384, United States
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Retina Consultants of Houston, PA
Houston, Texas, 77030, United States
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Retina Consultants of Orange County
Fullerton, California, 92835, United States
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Retina Group of New England - New London
Waterford, Connecticut, 06835, United States
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Retina Health Center
Fort Myers, Florida, 33907, United States
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Retina Health Center
Madison, Wisconsin, 53705, United States
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Retina Institute of California Medical Group
Palm Desert, California, 92260, United States
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Retina Northwest, PC
Portland, Oregon, 97221, United States
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Retina Research Center PLLC
Austin, Texas, 78750, United States
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Retina Specialty Institute
Pensacola, Florida, 32503, United States
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Retina Vitreous Center, PLLC
Edmond, Oklahoma, 73013, United States
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Retina Vitreous Consultants
Monroeville, Pennsylvania, 15146, United States
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Retina and Eye Consultantss
Hurstville, 2220, Australia
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Retina and Vitreous Associates of Kentucky, PSC dba Retina Associates of Kentucky
Lexington, Kentucky, 40509, United States
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Retina-Vitreous Associates Medical Group
Madison, Wisconsin, 53705, United States
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Retinal Diagnostic Center
Campbell, California, 95508, United States
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Retinal Research Institue, LLC
Phoenix, Arizona, 85014, United States
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Royal Liverpool University Hospital
Liverpool, L7 8XP, United Kingdom
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Rush University Medical Center
Chicago, Illinois, 60612, United States
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STZ Eyetrial
Tübingen, 72076, Germany
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Save Sight Institute
Westmead, 2145, Australia
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Sierra Eye Associates
Reno, Nevada, 89503, United States
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Southeast Retina Center, PC
Augusta, Georgia, 30909, United States
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Southern Eye Specialists
Christchurch, 8013, New Zealand
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Southwest Retina Research Center, LLC
Durango, Colorado, 81301, United States
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Spokane Eye Clinical Research
Spokane, Washington, 99204, United States
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St James's University Hospital
Leeds, West Yorkshire, LS9 7TF, United Kingdom
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Strathfield Retina Clinic
Strathfield, New South Wales, 2135, Australia
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Sunderland Eye Infirmary
Sunderland, SR2 9HP, United Kingdom
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Sydney Retina
Sydney, New South Wales, 2000, Australia
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Tel Aviv Sourasky Medical Center
Tel Aviv, 64239, Israel
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Tennessee Retina, PC
Nashville, Tennessee, 78503, United States
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Texas Retina Associates
Dallas, Texas, 75231, United States
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The Ashley Centre
Westmead, New South Wales, 2145, Australia
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The Ohio State University
Columbus, Ohio, 43212, United States
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The Retina Care Center
Baltimore, Maryland, 21209, United States
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The Retina Group of Washington
Chevy Chase, Maryland, 92705, United States
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The Retina Group of Washington
Fairfax, Virginia, 22031, United States
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The Retina Partners
Encino, California, 91436, United States
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Tufts Medical Center
Boston, Massachusetts, 02116, United States
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UNO-MED Centrum Medyne
Tarnów, 33-100, Poland
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Uni-medizin Gottingen Augenklinik 3.B1.261
Göttingen, 37075, Germany
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Uniklinik Koln
Cologne, 50937, Germany
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Universitats-Augenklinik Bonn
Bonn, 53127, Germany
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Universitatsklinikum Munster
Münster, 48149, Germany
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Universitatsklinikum Regensburg
Münster, 48145, Germany
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Universitatsklinikum Schleswig-Holstein
Lübeck, 23538, Germany
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University Opthalmology Clinic
Freiburg im Breisgau, 79106, Germany
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University hospital Kralovske Vinohrady
Prague, 10034, Czechia
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University of Ottawa Eye Institute
Ottawa, Ontario, K1H 8L6, Canada
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University of South Florida
Tampa, Florida, 33612, United States
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University of Utah - John A. Moran Center
Salt Lake City, Utah, 84312, United States
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University of Virginia
Charlottesville, Virginia, 22903, United States
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Valley Retina Institute
McAllen, Texas, 78503, United States
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Vision Research Center Eye Associates of NM
Albuquerque, New Mexico, 87109, United States
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Vitreoretinal Associates of Washington
Bellevue, Washington, 98004, United States
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Vitreoretinal Surgery
Minneapolis, Minnesota, 55435, United States
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Vitreous Retina Macula Consultants of New York
New York, New York, 10022, United States
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Vseobecna fakultni nemocnice v Praze
Prague, 2128 08, Czechia
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Western Carolina Retinal Associates
Asheville, North Carolina, 28803, United States
Conditions
Explore the condition pages connected to this study.