Chikungunya Vaccine's Long-Term shield put to the test

NCT ID NCT06007183

Ongoing ⭐️ VACCINE ⭐️ Sponsor: Bavarian Nordic Source: ClinicalTrials.gov ↗

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This phase 3 study follows healthy adults and adolescents who previously received a chikungunya vaccine in an earlier trial. It aims to see how long the vaccine's protection lasts and whether a booster shot can strengthen immunity years later. Participants will be monitored for up to five years, with some receiving a booster or placebo to compare immune responses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CHIKV VLP vaccine (also known as PXVX0317 or VIMKUNYA)
What this could lead to: If successful, this could confirm that a single chikungunya vaccine dose offers long-lasting protection, with a booster extending immunity for years.
What could go wrong: This is a follow-up study, so it won't prove the vaccine prevents disease on its own. The booster's benefit and long-term safety are still being evaluated, and results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chikungunya prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHIKUNGUNYA VIRUS INFECTION

Contacts and locations

Locations

Alliance for Multispecialty Research, LLC

Mobile, Alabama, 36608, United States
Alliance for Multispecialty Research, LLC

Tempe, Arizona, 85281, United States
Alliance for Multispecialty Research, LLC

Newton, Kansas, 67114, United States
Alliance for Multispecialty Research, LLC

Wichita, Kansas, 67207, United States
Alliance for Multispecialty Research, LLC

Lexington, Kentucky, 40509, United States
Alliance for Multispecialty Research, LLC

Kansas City, Missouri, 64114, United States
Alliance for Multispecialty Research, LLC

Las Vegas, Nevada, 89119, United States
Alliance for Multispecialty Research, LLC

Norfolk, Virginia, 23502, United States
BFHC Research, LLC

San Antonio, Texas, 78249, United States
DM Clinical Research

Houston, Texas, 77081, United States
DM Clinical Research

Tomball, Texas, 77375, United States
Lynn Institute of Norman

Norman, Oklahoma, 73072, United States
M3 Wake Research Inc.

Raleigh, North Carolina, 27612, United States
Optimal Research, LLC

Melbourne, Florida, 32934, United States
Optimal Research, LLC

Peoria, Illinois, 61614, United States
Rochester Clinical Research, LLC

Rochester, New York, 14609, United States
Suncoast Research Associates, LLC

Miami, Florida, 33173, United States
Synexus Clinical Research US, Inc.

Chicago, Illinois, 60602, United States
Velocity Clinical Research, Austin

Cedar Park, Texas, 78613, United States
Velocity Clinical Research, Cleveland

Cleveland, Ohio, 44122, United States
Velocity Clinical Research, Medford

Medford, Oregon, 97504, United States
Velocity Clinical Research, Providence

East Greenwich, Rhode Island, 02818, United States
Velocity Clinical Research, Salt Lake City

West Jordan, Utah, 84088, United States
Wr-Crcn, Llc

Las Vegas, Nevada, 89106, United States

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