New triple-drug combo aims to control cystic fibrosis long-term

NCT ID NCT05844449

ENROLLING_BY_INVITATION Disease control Sponsor: Vertex Pharmaceuticals Incorporated Source: ClinicalTrials.gov ↗

Summary

This study is testing the long-term safety and effectiveness of a three-drug combination therapy for people with cystic fibrosis aged 1 year and older. It follows participants who have already taken the medication in a previous trial to see how they do over a longer period. The main goals are to check for side effects and see if the treatment continues to help with lung function, weight gain, and reducing hospital visits.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

American Family Childrens Hospital

Madison, Wisconsin, 53792, United States
Ann & Robert H. Lurie Children's Hospital of Chicago - Hematology

Chicago, Illinois, 60611, United States
Boston Children's Hospital

Boston, Massachusetts, 02115, United States
British Columbia Children's Hospital

Vancouver, Canada
Charite Paediatric Pulmonology Department

Berlin, Germany
Children's Health Care d/b/a Children's Hospitals and Clinics of Minnesota

Minneapolis, Minnesota, 55404, United States
Children's Health Queensland Hospital and Health Service

South Brisbane, Australia
Children's Hospital of Colorado - Pulmonology

Aurora, Colorado, 80045, United States
Children's Hospital of Orange County

Orange, California, 92868, United States
Children's Hospital of Pittsburgh - Pulmonology

Pittsburgh, Pennsylvania, 15224, United States
Cincinnati Children's Hospital Medical Center - Pulmonology

Cincinnati, Ohio, 45229, United States
Cohen Children's Medical Center - Lakeville Road

Lake Success, New York, 11042, United States
Great Ormond Street Hospital for Children

London, United Kingdom
Hopital Femme Mere-Enfant

Bron, France
Hopital Necker Enfants Malades - Pulmonology

Paris, France
Hospital for Sick Children - Pulmonology

Toronto, Canada
Inselspital Bern

Bern, Switzerland
JW Riley Hospital for Children - Pulmonology

Indianapolis, Indiana, 46202, United States
Karolinska University Hospital - Pulmonology

Stockholm, Sweden
Kinderspital Zurich - Abteilung Pneumologie

Zurich, Switzerland
Medizinische Hochschule Hannover - Clinic for Pediatric Pneumology, Allergology and Neonatology, CF-Centre

Hanover, Germany
Nationwide Children's Hospital

Columbus, Ohio, 43205, United States
Noah's Ark Children's Hospital for Wales

Cardiff, United Kingdom
Sahlgrenska Universitetssjukhuset - Göteborg CF-center

Gothenburg, Sweden
Sophia Children's Hospital

Rotterdam, Netherlands
St. Louis Children's Hospital - Pulmonology

St Louis, Missouri, 63110, United States
Stanford University - Palo Alto - Pulmonology

Palo Alto, California, 94304, United States
Starship Child Health

Grafton, New Zealand
Texas Children's Hospital - Wallace Tower - Pulmonology

Houston, Texas, 77030, United States
The Children's Mercy Hospital

Kansas City, Missouri, 64108, United States
The Emory Clinic - Clifton Road - Pulmonology

Atlanta, Georgia, 30322, United States
The Kids Research Institute Australia

Nedlands, Australia
The Royal Children's Hospital Melbourne

Parkville, Australia
UH Cleveland Medical Center - Pulmonology

Cleveland, Ohio, 44106, United States
Universitatsklinikum Essen

Essen, Germany
Vermont Lung Center

Colchester, Vermont, 05446, United States
Women's & Children's Hospital

North Adelaide, Australia

Conditions

Explore the condition pages connected to this study.

CYSTIC FIBROSIS