Three-drug combo shows promise for long-term cystic fibrosis control
NCT ID NCT05153317
Summary
This study followed cystic fibrosis patients aged 2 and older to see how safe and effective a three-drug combination therapy is over the long term. Participants had previously taken these medications in an earlier study and continued treatment to monitor their response. The research measured lung function, sweat chloride levels, and tracked any side effects to understand the therapy's ongoing benefits and risks.
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Contacts and locations
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Locations
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Alder Hey Children's NHS Foundation Trust
Liverpool, United Kingdom
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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Banner University of Arizona Medical Center
Tucson, Arizona, 85724, United States
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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British Columbia Children's Hospital
Vancouver, Canada
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Charite Paediatric Pulmonology Department
Berlin, Germany
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Children's Hospital of Colorado
Aurora, Colorado, 80045, United States
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Children's Respiratory and Critical Care Specialists, P.A., Children's Hospitals and Clinics of Minnesota
Minneapolis, Minnesota, 55404, United States
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NC TraCS Institute - CTRC University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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Queensland Children's Hospital
South Brisbane, Australia
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Riley Hospital for Children at Indiana University Health
Indianapolis, Indiana, 46202, United States
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Royal Brompton Hospital
London, United Kingdom
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Seattle Children's Hospital
Seattle, Washington, 98105, United States
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Stanford University
Palo Alto, California, 94304, United States
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Telethon Kids Institute
Nedlands, Australia
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The Children's Mercy Hospital
Kansas City, Missouri, 64108, United States
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The Hospital for Sick Children
Toronto, Canada
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The Royal Children's Hospital
Parkville, Australia
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UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States
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Universitatsklinikum Essen (AoR), Kinderklinik III, Abt. fur Pneumologie
Essen, Germany
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Washington University School of Medicine / St. Louis Children's Hospital
St Louis, Missouri, 63110, United States
Conditions
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