Daily shot shows promise for helping kids with dwarfism grow

NCT ID NCT03989947

First seen Mar 20, 2026 · Last updated May 12, 2026 · Updated 6 times

Summary

This study looks at the long-term safety and effectiveness of a daily injection called BMN 111 in children with achondroplasia, the most common form of dwarfism. About 73 children who completed a previous year-long study will receive the drug until they reach near-adult height. The goal is to see if the treatment helps improve growth and is safe over time.

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Contacts and locations

Locations

  • Alfred I. duPont Hospital for Children

    Wilmington, Delaware, 19803, United States

  • Ann Robert and H. Lurie Children's Hospital of Chicago

    Chicago, Illinois, 60611, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Children's Hospital & Research Center Oakland

    Oakland, California, 94609, United States

  • Cincinnati Childrens Hospital

    Cincinnati, Ohio, 45229, United States

  • Emory University

    Decatur, Georgia, 30033, United States

  • Guy's and St. Thomas NHS Foundation Trust Evelina Children's Hospital

    London, SE19RT, United Kingdom

  • Harbor - UCLA Medical Center

    Torrance, California, 90509, United States

  • Medical College of Wisconsin, Children's Hospital

    Milwaukee, Wisconsin, 53226, United States

  • Murdoch Children's Research Institute

    Parkville, Victoria, 3052, Australia

  • Osaka University

    Osaka, 565-0871, Japan

  • Saitama Children's Medical Center

    Saitama, 330-8777, Japan

  • Sheffield Children's NHS Foundation Trust

    Sheffield, S102TH, United Kingdom

  • The Children's Hospital at Westmead

    Westmead, New South Wales, 2145, Australia

  • Tokushima University Hospital

    Tokushima, 77-8503, Japan

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232-2578, United States

Conditions

Explore the condition pages connected to this study.