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Can a single surgery fix ankle cartilage for a decade? a long-term study puts AMIC to the test.
NCT ID NCT07725770
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This study looks at how well a surgical technique called AMIC holds up ten years after repairing cartilage damage in the ankle. Researchers are checking whether the pain relief and function patients gained in the first few years remain stable or fade over time. About 40 people who had the procedure between 2013 and 2016 are being followed up to see if the benefits last.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- autologous matrix-induced chondrogenesis (AMIC) using a porcine collagen I/III membrane
- What this could lead to
- If successful, this could confirm that the AMIC procedure provides lasting relief for ankle cartilage defects, reducing the need for more invasive surgeries.
- What could go wrong
- This is a small, single-center study with only 40 patients, and long-term outcomes may vary. The procedure involves surgery and recovery risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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IRCCS Ospedale Galeazzi-Sant'Ambrogio
Milan, Italy