Cancer drug adagrasib offers continued hope in rollover trial

NCT ID NCT07415031

Recruiting now Disease control Sponsor: Mirati Therapeutics Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study provides ongoing treatment with the cancer drug adagrasib (BMS-986503) to patients with advanced solid tumors who have already seen benefit in earlier studies. About 170 adults with non-small cell lung cancer, colorectal cancer, or other solid tumors can join if they are still benefiting from the drug. The main goal is to monitor side effects and safety over the long term.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMORS

Contacts and locations

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Study contacts

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Phone: •••-•••-•••• Email: •••••@•••••
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Locations

Florida Cancer Specialists - North
RECRUITING

St. Petersburg, Florida, 33701, United States

Contact Phone: •••-•••-••••
Local Institution - 0003
WITHDRAWN

Newark, Delaware, 19713, United States
Local Institution - 0005
WITHDRAWN

Phoenix, Arizona, 85054, United States
Local Institution - 0006
NOT_YET_RECRUITING

Badalona, Barcelona, 08916, Spain

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Local Institution - 0007
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A Coruña, A Coruña [La Coruña], 15006, Spain

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Local Institution - 0008
NOT_YET_RECRUITING

Seville, 41009, Spain

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Local Institution - 0009
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Pamplona, Navarre, 31008, Spain

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Local Institution - 0010
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Barcelona, Barcelona [Barcelona], 08028, Spain

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Local Institution - 0011
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Palma, Balears [Baleares], 07120, Spain

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Local Institution - 0012
NOT_YET_RECRUITING

München, 81737, Germany

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Local Institution - 0013
NOT_YET_RECRUITING

Bellingham, Washington, 98225, United States

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Local Institution - 0014
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Lisbon, Lisbon District, 1099-023, Portugal

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Local Institution - 0015
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Madrid, 28040, Spain

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Local Institution - 0018
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Málaga, 29011, Spain

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Local Institution - 0019
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Rome, Roma, 00144, Italy

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Local Institution - 0020
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Orbassano, 10043, Italy

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Local Institution - 0021
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Milan, 20141, Italy

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Local Institution - 0022
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Attiki, 18547, Greece

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Local Institution - 0023
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Germantown, Tennessee, 38138, United States

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Local Institution - 0024
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Madrid, Madrid, Comunidad de, 28034, Spain

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Local Institution - 0026
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Terni (Perugia), 6156, Italy

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Local Institution - 0027
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Córdoba, 14004, Spain

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Local Institution - 0029
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Barcelona, 08035, Spain

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Local Institution - 0030
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Santander, Cantabria, 39008, Spain

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Local Institution - 0031
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Roma, 00168, Italy

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Local Institution - 0032
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Angers, Maine-et-Loire, 49055, France

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Local Institution - 0033
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Ghent, 9000, Belgium

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Local Institution - 0034
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Amsterdam, 1006 BE, Netherlands

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Local Institution - 0035
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Harderwijk, 3844 DG, Netherlands

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Local Institution - 0036
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Omaha, Nebraska, 68114, United States

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Local Institution - 0037
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Beijing, Beijing Municipality, 100142, China

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Local Institution - 0038
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Changsha, Hunan, 410031, China

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Local Institution - 0039
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Jinan, Shandong, 250117, China

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Local Institution - 0040
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Chengdu, Sichuan, 610041, China

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Local Institution - 0041
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Xi'an, 710061, China

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Local Institution - 0042
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Zhengzhou, Henan, 450008, China

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Local Institution - 0043
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Shanghai, Shanghai Municipality, 200032, China

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Local Institution - 0044
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Hangzhou, Zhejiang, 310022, China

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Local Institution - 0045
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Xiamen, Fujian, 361003, China

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Local Institution - 0046
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Nanjing, Jiangsu, 210012, China

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Local Institution - 0047
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Linyi, Shandong, 276000, China

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Local Institution - 0048
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Nanchang, Jiangxi, 330006, China

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Local Institution - 0049
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Shenyang, Liaoning, 110001, China

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Local Institution - 0050
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Saint-Herblain, Loire-Atlantique, 44805, France

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Local Institution - 0051
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Poitiers, Vienne, 86021, France

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Local Institution - 0052
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Meldola, 47014, Italy

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Local Institution - 0053
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Bologna, 40138, Italy

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Local Institution - 0054
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Florence, 50139, Italy

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Local Institution - 0055
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Jerusalem, Jerusalem, 9103102, Israel

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Local Institution - 0056
NOT_YET_RECRUITING

Breda, North Brabant, 4818 CK, Netherlands

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Local Institution - 0058
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Quimper, 29000, France

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Local Institution - 0059
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Marseille, 13915, France

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Local Institution - 0060
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Craiova, Dolj, 200746, Romania

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Local Institution - 0061
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Paris, Île-de-France Region, 75014, France

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Local Institution - 0062
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Madrid, 28041, Spain

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Local Institution - 0063
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Saint-Herblain, Loire-Atlantique, 44800, France

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Local Institution - 0065
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La Tronche, Isère, 38700, France

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Local Institution - 0067
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Budapest, 1122, Hungary

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Local Institution - 0068
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Seoul, 120-752, South Korea

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Local Institution - 0069
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Gyeonggi-do, 410-769, South Korea

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Local Institution - 0070
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Seoul, 06351, South Korea

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Local Institution - 0071
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Utrecht, 3543 AZ, Netherlands

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Local Institution - 0072
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Vancouver, British Columbia, V5Z 4E6, Canada

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Local Institution - 0073
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Saint Paul, Minnesota, 55101, United States

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Local Institution - 0074
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Strasbourg, Alsace, 67091, France

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Local Institution - 0075
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Gleizé, Rhône, 69400, France

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Local Institution - 0076
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Nice, Alpes-Maritimes, 06000, France

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Local Institution - 0077
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Tours, 37032, France

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Local Institution - 0078
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Saint-Mandé, 94163, France

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Local Institution - 0079
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Pesaro, 61122, Italy

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Local Institution - 0080
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Boston, Massachusetts, 02215, United States

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Local Institution - 0081
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Athens, Attikí, 115 28, Greece

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Local Institution - 0082
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Long Beach, California, 90806, United States

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Local Institution - 0083
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Madrid, 28007, Spain

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Local Institution - 0084
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Valencia, Valenciana, Comunitat, 46010, Spain

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Local Institution - 0085
NOT_YET_RECRUITING

Créteil, 94010, France

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Local Institution - 0086
NOT_YET_RECRUITING

Nice, Alpes-Maritimes, 06189, France

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Local Institution - 0087
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Thessaloniki, 54639, Greece

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Local Institution - 0088
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Singapore, Central Singapore, 168583, Singapore

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Local Institution - 0089
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Budapest, 1121, Hungary

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Local Institution - 0090
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Bron, Rhône, 69677, France

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Local Institution - 0091
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Besançon, Doubs, 25000, France

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Local Institution - 0092
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Boston, Massachusetts, 00215, United States

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Local Institution - 0093
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St Leonards, New South Wales, 2065, Australia

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Local Institution - 0101
NOT_YET_RECRUITING

Lublin, 20-064, Poland

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Local Institution - 0102
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Gdansk, 80-214, Poland

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Local Institution - 0103
NOT_YET_RECRUITING

Pessac, Aquitaine, 33600, France

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Local Institution - 0106
NOT_YET_RECRUITING

Tel Aviv, 6423906, Israel

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Local Institution - 0107
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Milan, 20141, Italy

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Local Institution - 0110
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Tōon, Ehime, 791-0295, Japan

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Local Institution - 0112
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Wichita, Kansas, 67208, United States

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Local Institution - 0113
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Birmingham, B9 5SS, United Kingdom

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Local Institution - 0114
NOT_YET_RECRUITING

Leicester, LE1 5WW, United Kingdom

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Local Institution - 0115
NOT_YET_RECRUITING

London, London, City of, SE1 9RT, United Kingdom

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Mayo Clinic in Rochester, Minnesota
RECRUITING

Rochester, Minnesota, 55905, United States

Contact Phone: •••-•••-••••
Oncology Associates Of Oregon, Pc
RECRUITING

Eugene, Oregon, 97401, United States

Contact Phone: •••-•••-••••
Southern California Permanente Medical Group
RECRUITING

Bellflower, California, 90706, United States

Contact Phone: •••-•••-••••
Texas Oncology - Baylor Charles A. Sammons Cancer Center
RECRUITING

Dallas, Texas, 75246, United States

Contact Phone: •••-•••-••••
Texas Oncology - DFW
RECRUITING

Grapevine, Texas, 76051, United States

Contact Phone: •••-•••-••••
Texas Oncology-Bedford
RECRUITING

Bedford, Texas, 76022, United States

Contact Phone: •••-•••-••••