Cancer drug adagrasib offers continued hope in rollover trial

NCT ID NCT07415031

Recruiting now Disease control Sponsor: Mirati Therapeutics Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 4 times

Summary

This study provides ongoing treatment with the cancer drug adagrasib (BMS-986503) to patients with advanced solid tumors who have already seen benefit in earlier studies. About 170 adults with non-small cell lung cancer, colorectal cancer, or other solid tumors can join if they are still benefiting from the drug. The main goal is to monitor side effects and safety over the long term.

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Conditions

The condition(s) this trial relates to.

colorectal cancer neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMORS

Contacts and locations

Locations

Florida Cancer Specialists - North
RECRUITING

St. Petersburg, Florida, 33701, United States
Local Institution - 0003
WITHDRAWN

Newark, Delaware, 19713, United States
Local Institution - 0005
WITHDRAWN

Phoenix, Arizona, 85054, United States
Local Institution - 0006
NOT_YET_RECRUITING

Badalona, Barcelona, 08916, Spain
Local Institution - 0007
NOT_YET_RECRUITING

A Coruña, A Coruña [La Coruña], 15006, Spain
Local Institution - 0008
NOT_YET_RECRUITING

Seville, 41009, Spain
Local Institution - 0009
NOT_YET_RECRUITING

Pamplona, Navarre, 31008, Spain
Local Institution - 0010
NOT_YET_RECRUITING

Barcelona, Barcelona [Barcelona], 08028, Spain
Local Institution - 0011
NOT_YET_RECRUITING

Palma, Balears [Baleares], 07120, Spain
Local Institution - 0012
NOT_YET_RECRUITING

München, 81737, Germany
Local Institution - 0013
NOT_YET_RECRUITING

Bellingham, Washington, 98225, United States
Local Institution - 0014
NOT_YET_RECRUITING

Lisbon, Lisbon District, 1099-023, Portugal
Local Institution - 0015
NOT_YET_RECRUITING

Madrid, 28040, Spain
Local Institution - 0018
NOT_YET_RECRUITING

Málaga, 29011, Spain
Local Institution - 0019
NOT_YET_RECRUITING

Rome, Roma, 00144, Italy
Local Institution - 0020
NOT_YET_RECRUITING

Orbassano, 10043, Italy
Local Institution - 0021
NOT_YET_RECRUITING

Milan, 20141, Italy
Local Institution - 0022
NOT_YET_RECRUITING

Attiki, 18547, Greece
Local Institution - 0024
NOT_YET_RECRUITING

Madrid, Madrid, Comunidad de, 28034, Spain
Local Institution - 0026
NOT_YET_RECRUITING

Terni (Perugia), 6156, Italy
Local Institution - 0027
NOT_YET_RECRUITING

Córdoba, 14004, Spain
Local Institution - 0029
NOT_YET_RECRUITING

Barcelona, 08035, Spain
Local Institution - 0030
NOT_YET_RECRUITING

Santander, Cantabria, 39008, Spain
Local Institution - 0031
NOT_YET_RECRUITING

Roma, 00168, Italy
Local Institution - 0032
NOT_YET_RECRUITING

Angers, Maine-et-Loire, 49055, France
Local Institution - 0033
NOT_YET_RECRUITING

Ghent, 9000, Belgium
Local Institution - 0034
NOT_YET_RECRUITING

Amsterdam, 1006 BE, Netherlands
Local Institution - 0035
NOT_YET_RECRUITING

Harderwijk, 3844 DG, Netherlands
Local Institution - 0036
NOT_YET_RECRUITING

Omaha, Nebraska, 68114, United States
Local Institution - 0037
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100142, China
Local Institution - 0038
NOT_YET_RECRUITING

Changsha, Hunan, 410031, China
Local Institution - 0039
NOT_YET_RECRUITING

Jinan, Shandong, 250117, China
Local Institution - 0040
NOT_YET_RECRUITING

Chengdu, Sichuan, 610041, China
Local Institution - 0041
NOT_YET_RECRUITING

Xi'an, 710061, China
Local Institution - 0042
NOT_YET_RECRUITING

Zhengzhou, Henan, 450008, China
Local Institution - 0043
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, 200032, China
Local Institution - 0044
NOT_YET_RECRUITING

Hangzhou, Zhejiang, 310022, China
Local Institution - 0045
NOT_YET_RECRUITING

Xiamen, Fujian, 361003, China
Local Institution - 0046
NOT_YET_RECRUITING

Nanjing, Jiangsu, 210012, China
Local Institution - 0047
NOT_YET_RECRUITING

Linyi, Shandong, 276000, China
Local Institution - 0048
NOT_YET_RECRUITING

Nanchang, Jiangxi, 330006, China
Local Institution - 0049
NOT_YET_RECRUITING

Shenyang, Liaoning, 110001, China
Local Institution - 0050
NOT_YET_RECRUITING

Saint-Herblain, Loire-Atlantique, 44805, France
Local Institution - 0051
NOT_YET_RECRUITING

Poitiers, Vienne, 86021, France
Local Institution - 0052
NOT_YET_RECRUITING

Meldola, 47014, Italy
Local Institution - 0053
NOT_YET_RECRUITING

Bologna, 40138, Italy
Local Institution - 0054
NOT_YET_RECRUITING

Florence, 50139, Italy
Local Institution - 0055
NOT_YET_RECRUITING

Jerusalem, Jerusalem, 9103102, Israel
Local Institution - 0056
NOT_YET_RECRUITING

Breda, North Brabant, 4818 CK, Netherlands
Local Institution - 0058
NOT_YET_RECRUITING

Quimper, 29000, France
Local Institution - 0059
NOT_YET_RECRUITING

Marseille, 13915, France
Local Institution - 0060
NOT_YET_RECRUITING

Craiova, Dolj, 200746, Romania
Local Institution - 0061
NOT_YET_RECRUITING

Paris, Île-de-France Region, 75014, France
Local Institution - 0062
NOT_YET_RECRUITING

Madrid, 28041, Spain
Local Institution - 0063
NOT_YET_RECRUITING

Saint-Herblain, Loire-Atlantique, 44800, France
Local Institution - 0065
NOT_YET_RECRUITING

La Tronche, Isère, 38700, France
Local Institution - 0067
NOT_YET_RECRUITING

Budapest, 1122, Hungary
Local Institution - 0068
NOT_YET_RECRUITING

Seoul, 120-752, South Korea
Local Institution - 0069
NOT_YET_RECRUITING

Gyeonggi-do, 410-769, South Korea
Local Institution - 0070
NOT_YET_RECRUITING

Seoul, 06351, South Korea
Local Institution - 0071
NOT_YET_RECRUITING

Utrecht, 3543 AZ, Netherlands
Local Institution - 0072
NOT_YET_RECRUITING

Vancouver, British Columbia, V5Z 4E6, Canada
Local Institution - 0073
NOT_YET_RECRUITING

Saint Paul, Minnesota, 55101, United States
Local Institution - 0074
NOT_YET_RECRUITING

Strasbourg, Alsace, 67091, France
Local Institution - 0075
NOT_YET_RECRUITING

Gleizé, Rhône, 69400, France
Local Institution - 0076
NOT_YET_RECRUITING

Nice, Alpes-Maritimes, 06000, France
Local Institution - 0077
NOT_YET_RECRUITING

Tours, 37032, France
Local Institution - 0078
NOT_YET_RECRUITING

Saint-Mandé, 94163, France
Local Institution - 0079
NOT_YET_RECRUITING

Pesaro, 61122, Italy
Local Institution - 0080
NOT_YET_RECRUITING

Boston, Massachusetts, 02215, United States
Local Institution - 0081
NOT_YET_RECRUITING

Athens, Attikí, 115 28, Greece
Local Institution - 0082
NOT_YET_RECRUITING

Long Beach, California, 90806, United States
Local Institution - 0083
NOT_YET_RECRUITING

Madrid, 28007, Spain
Local Institution - 0084
NOT_YET_RECRUITING

Valencia, Valenciana, Comunitat, 46010, Spain
Local Institution - 0085
NOT_YET_RECRUITING

Créteil, 94010, France
Local Institution - 0086
NOT_YET_RECRUITING

Nice, Alpes-Maritimes, 06189, France
Local Institution - 0087
NOT_YET_RECRUITING

Thessaloniki, 54639, Greece
Local Institution - 0088
NOT_YET_RECRUITING

Singapore, Central Singapore, 168583, Singapore
Local Institution - 0089
NOT_YET_RECRUITING

Budapest, 1121, Hungary
Local Institution - 0090
NOT_YET_RECRUITING

Bron, Rhône, 69677, France
Local Institution - 0091
NOT_YET_RECRUITING

Besançon, Doubs, 25000, France
Local Institution - 0092
NOT_YET_RECRUITING

Boston, Massachusetts, 00215, United States
Local Institution - 0093
NOT_YET_RECRUITING

St Leonards, New South Wales, 2065, Australia
Local Institution - 0101
NOT_YET_RECRUITING

Lublin, 20-064, Poland
Local Institution - 0102
NOT_YET_RECRUITING

Gdansk, 80-214, Poland
Local Institution - 0103
NOT_YET_RECRUITING

Pessac, Aquitaine, 33600, France
Local Institution - 0106
NOT_YET_RECRUITING

Tel Aviv, 6423906, Israel
Local Institution - 0107
NOT_YET_RECRUITING

Milan, 20141, Italy
Local Institution - 0110
NOT_YET_RECRUITING

Tōon, Ehime, 791-0295, Japan
Local Institution - 0112
NOT_YET_RECRUITING

Wichita, Kansas, 67208, United States
Local Institution - 0113
NOT_YET_RECRUITING

Birmingham, B9 5SS, United Kingdom
Local Institution - 0114
NOT_YET_RECRUITING

Leicester, LE1 5WW, United Kingdom
Local Institution - 0115
NOT_YET_RECRUITING

London, London, City of, SE1 9RT, United Kingdom
Local Institution - 0119
NOT_YET_RECRUITING

Haifa, 31048, Israel
Mayo Clinic in Rochester, Minnesota
RECRUITING

Rochester, Minnesota, 55905, United States
Oncology Associates Of Oregon, Pc
RECRUITING

Eugene, Oregon, 97401, United States
Southern California Permanente Medical Group
RECRUITING

Bellflower, California, 90706, United States
Texas Oncology - Baylor Charles A. Sammons Cancer Center
RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology - DFW
RECRUITING

Grapevine, Texas, 76051, United States
Texas Oncology-Bedford
RECRUITING

Bedford, Texas, 76022, United States
The West Clinic, PLLC dba West Cancer Center
RECRUITING

Germantown, Tennessee, 38138, United States

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