New combo therapy aims to stall advanced cancers

NCT ID NCT06825494

First seen Jan 07, 2026 · Last updated May 15, 2026 · Updated 12 times

Summary

This study tests a new drug called LM-108, given with other cancer drugs (penpulimab and chemotherapy), in people with advanced solid tumors that have not responded to prior treatments. The goal is to find a safe dose and see if the combination can shrink tumors or delay their growth. About 194 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Anhui Provincial Cancer Hospital

    NOT_YET_RECRUITING

    Hefei, Anhui, 230031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cancer Hospital of Shandong First Medical University

    NOT_YET_RECRUITING

    Jinan, Shandong, 264000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • First Hospital of Shangxi Medical University

    NOT_YET_RECRUITING

    Taiyuan, Shangxi, 030001, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fudan University Shanghai Cancer Center

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fujian Cancer Hospital

    NOT_YET_RECRUITING

    Fuzhou, Fujian, 350014, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gansu Wuwei Tumour Hospital

    NOT_YET_RECRUITING

    Wuwei, Gansu, 733099, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guangxi Medical University Cancer Hospital

    NOT_YET_RECRUITING

    Nanning, Guangxi, 530021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Harbin Medical University Cancer Hospital

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, 150040, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hubei Cancer Hospital

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430079, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Inner Mongolia Hospital of Peking University Cancer Hospita

    NOT_YET_RECRUITING

    Hohhot, Inner Mongolia, 010000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jiangsu Provincial People's Hospital

    NOT_YET_RECRUITING

    Nanjing, Jiangsu, 210000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jilin Cancer Hospital

    NOT_YET_RECRUITING

    Changchun, Jilin, 130000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NanJing Drum Tower Hospital

    NOT_YET_RECRUITING

    Nanjing, Jiangsu, 210000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nanyang Second General Hospital

    NOT_YET_RECRUITING

    Nanyang, Henan, 473012, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking University Shenzhen Hospita

    NOT_YET_RECRUITING

    Shenzhen, Guangdong, 518000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ping mei shen ma Medical Group General Hospital

    RECRUITING

    Pingdingshan, Henan, 467000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Renji Hospital, Shanghai Jiaotong University School of Medicine

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200120, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanxi Cancer Hospital

    NOT_YET_RECRUITING

    Taiyuan, Shanxi, 030000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sichuan Cancer Hospita

    NOT_YET_RECRUITING

    Chengdu, Sichuan, 610042, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tangshan People's Hospital

    NOT_YET_RECRUITING

    Tangshan, Hebei, 063001, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Soochow University

    NOT_YET_RECRUITING

    Suzhou, Jiangsu, 215006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Wenzhou Medical University

    NOT_YET_RECRUITING

    Wenzhou, Zhejiang, 325005, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Xi'an Jiaotong University Medical College

    NOT_YET_RECRUITING

    Xi'an, Shaanxi, 710000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Zhengzhou University

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450002, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital Of China Medical University

    NOT_YET_RECRUITING

    Shenyang, Liaoning, 110000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of Lanzhou University

    NOT_YET_RECRUITING

    Lanzhou, Gansu, 730030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Hospital of Anhui Medical University

    NOT_YET_RECRUITING

    Hefei, Anhui, 230601230601, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The second xiangya hospital of central south university

    NOT_YET_RECRUITING

    Changsha, Hunan, 410011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University Cancer Institute & Hospital

    NOT_YET_RECRUITING

    Tianjin, Tianjin Municipality, 300000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xinjiang Medical University Affiliated Cancer Hospital

    NOT_YET_RECRUITING

    Ürümqi, Xinjiang, 830054, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • XuZhou Central Hospital

    NOT_YET_RECRUITING

    Xuzhou, Jiangsu, 221000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.