Experimental injections target liver damage in rare genetic disorder

NCT ID NCT02900183

Summary

This study aimed to test whether multiple doses of an experimental drug called ARC-AAT could safely reduce the buildup of a harmful protein in the livers of adults with Alpha-1 Antitrypsin Deficiency. Participants would have received seven intravenous injections and undergone two liver biopsies to measure the drug's effect. The trial was withdrawn before any patients were enrolled.

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Contacts and locations

Locations

  • Research Site 1

    Toronto, Ontario, M5T3A9, Canada

  • Research Site 2

    Dublin, Ireland

  • Research Site 3

    Pavia, 27100, Italy

  • Research Site 4

    Malmo, SE-205 02, Sweden

Conditions

Explore the condition pages connected to this study.