Liver function may change how this drug works
NCT ID NCT05661344
First seen Jan 06, 2026
Summary
This study looks at how the drug BI 1015550 is processed in people with mild or moderate liver problems compared to those with healthy livers. 28 adults will take a single dose and have their blood levels measured over time. The goal is to see if liver impairment changes drug exposure, which could guide future dosing recommendations.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CRS Clinical Research Services Kiel GmbH
Kiel, 24105, Germany
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BI 1015550 (Nerandomilast)
What this could lead to
If successful, this study will help doctors understand how to dose BI 1015550 safely for patients with liver problems.
What could go wrong
This is a very early, small study (28 participants) focused on drug levels, not on treating a disease. Results may not apply to all patients or predict real-world outcomes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.