Radiation boost tested to fight tough liver cancer

NCT ID NCT01730937

Completed Disease control Sponsor: Radiation Therapy Oncology Group Source: ClinicalTrials.gov ↗

Summary

This study tested if adding a precise, high-dose radiation treatment (SBRT) to the standard drug sorafenib works better than using the drug alone for adults with advanced liver cancer. It involved 193 participants whose cancer was not suitable for surgery or other common treatments. The main goal was to see if the combination helped people live longer.

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Contacts and locations

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Locations

Alta Bates Summit Medical Center-Herrick Campus

Berkeley, California, 94704, United States
Boston Medical Center

Boston, Massachusetts, 02118, United States
CHUM - Centre Hospitalier de l'Universite de Montreal

Montreal, Quebec, H2X 3E4, Canada
CHUM - Hopital Notre-Dame

Montreal, Quebec, H2L 4M1, Canada
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Columbia University/Herbert Irving Cancer Center

New York, New York, 10032, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Froedtert and the Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Hunter Holmes McGuire Veterans Administration Medical Center

Richmond, Virginia, 23249, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Indiana University/Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Juravinski Cancer Centre at Hamilton Health Sciences

Hamilton, Ontario, L8V 5C2, Canada
London Regional Cancer Program

London, Ontario, N6A 4L6, Canada
Loyola University Medical Center

Maywood, Illinois, 60153, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Montefiore Medical Center - Moses Campus

The Bronx, New York, 10467, United States
Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555, United States
Northwestern University

Chicago, Illinois, 60611, United States
Ochsner Medical Center Jefferson

New Orleans, Louisiana, 70121, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Pamela Youde Nethersole Eastern Hospital

Chai Wan, Hong Kong
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States
Peter MacCallum Cancer Centre

Melbourne, Victoria, 3000, Australia
ProCure Proton Therapy Center-Seattle

Seattle, Washington, 98133, United States
Providence Portland Medical Center

Portland, Oregon, 97213, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
Saint Vincent's Medical Center

Bridgeport, Connecticut, 06606, United States
Samsung Medical Center

Seoul, Korea, 135-710, South Korea
Stony Brook University Medical Center

Stony Brook, New York, 11794, United States
The Research Institute of the McGill University Health Centre (MUHC)

Montreal, Quebec, H3H 2R9, Canada
Tom Baker Cancer Centre

Calgary, Alberta, T2N 4N2, Canada
UCSF Medical Center-Mission Bay

San Francisco, California, 94158, United States
UCSF Medical Center-Mount Zion

San Francisco, California, 94115, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
University Health Network-Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada
University of Colorado Hospital

Aurora, Colorado, 80045, United States
University of Illinois

Chicago, Illinois, 60612, United States
University of Maryland/Greenebaum Cancer Center

Baltimore, Maryland, 21201, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136, United States
University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Mississippi Medical Center

Jackson, Mississippi, 39216, United States
University of Pennsylvania/Abramson Cancer Center

Philadelphia, Pennsylvania, 19104, United States
University of Rochester

Rochester, New York, 14642, United States
University of Vermont Medical Center

Burlington, Vermont, 05401, United States
University of Washington Medical Center

Seattle, Washington, 98195, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.

ADULT PRIMARY HEPATOCELLULAR CARCINOMA ADVANCED ADULT PRIMARY LIVER CANCER RECURRENT ADULT PRIMARY LIVER CANCER