Could an ADHD drug clear the brain fog of chronic fatigue syndrome?
NCT ID NCT01071044
First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 23 times
Summary
This study tested the drug lisdexamfetamine (a stimulant used for ADHD) in 26 adults with chronic fatigue syndrome who also had cognitive problems like poor memory or focus. Participants received either the drug or a placebo for several weeks. The goal was to see if the drug could improve thinking skills and reduce fatigue. Results suggested some benefit in executive function (planning, organizing) and fatigue severity, but the study was small and more research is needed.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Rochester Center for Behavioral Medicine
Rochester Hills, Michigan, 48307, United States
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