New drug targets genetic driver in advanced cancers

NCT ID NCT07359820

Summary

This study is testing whether an experimental drug called lirafugratinib can help control advanced solid tumors that have a specific genetic change called FGFR2 fusion or rearrangement. The trial is for adults whose cancer has spread or cannot be surgically removed and who have already tried at least one other treatment. Participants will take the oral medication regularly while doctors monitor how their tumors respond and track any side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Georges François Leclerc

    Dijon, 21079, France

  • Centre Leon Berard

    Lyon, 69373, France

  • Gustave Roussy Cancer Campus

    Paris, 94805, France

  • Hospital Universitario Fundación Jiménez Díaz- START MADRID

    Madrid, 28040, Spain

  • Hospital Universitario HM Sanchinarro-START MADRID-CIOCC

    Madrid, 28050, Spain

  • Institut Bergonie

    Bordeaux, 33076, France

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10022, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • START Barcelona-Hospital HM Nou Delfos

    Barcelona, 08023, Spain

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Sarah Cannon Research Institute UK

    London, W1G 6AD, United Kingdom

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • The University of Texas M.D. Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of Chicago Medical Center

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.