New targeted drug shows promise for rare gene-driven cancers

NCT ID NCT07359820

First seen Jan 23, 2026 · Last updated May 06, 2026 · Updated 12 times

Summary

This study tests an experimental drug called lirafugratinib in adults with advanced solid tumors (except bile duct cancer) that have a specific FGFR2 gene fusion or rearrangement. Participants take the drug by mouth and visit the clinic for regular checkups. The goal is to see if the drug shrinks tumors and how safe it is.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Georges François Leclerc

    NOT_YET_RECRUITING

    Dijon, 21079, France

  • Centre Leon Berard

    NOT_YET_RECRUITING

    Lyon, 69373, France

  • Gustave Roussy Cancer Campus

    NOT_YET_RECRUITING

    Paris, 94805, France

  • Hospital Universitario Fundación Jiménez Díaz- START MADRID

    NOT_YET_RECRUITING

    Madrid, 28040, Spain

  • Hospital Universitario HM Sanchinarro-START MADRID-CIOCC

    NOT_YET_RECRUITING

    Madrid, 28050, Spain

  • Institut Bergonie

    NOT_YET_RECRUITING

    Bordeaux, 33076, France

  • Massachusetts General Hospital

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    NOT_YET_RECRUITING

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic

    NOT_YET_RECRUITING

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic

    NOT_YET_RECRUITING

    Rochester, Minnesota, 55905, United States

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact Phone: •••-•••-••••

    Contact

  • START Barcelona-Hospital HM Nou Delfos

    NOT_YET_RECRUITING

    Barcelona, 08023, Spain

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Sarah Cannon Research Institute UK

    NOT_YET_RECRUITING

    London, W1G 6AD, United Kingdom

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • The Christie NHS Foundation

    NOT_YET_RECRUITING

    Manchester, M20 4GJ, United Kingdom

  • The University of Texas M.D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-••••

  • University College Hospital (NIHR UCLH Clinical Research Facility)

    NOT_YET_RECRUITING

    London, NW1 2BU, United Kingdom

  • University of Chicago Medical Center

    NOT_YET_RECRUITING

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.