Could a common IBS drug help fight colon cancer?
NCT ID NCT03796884
Summary
This study is testing whether a 7-day course of the drug linaclotide can produce biological changes in colon polyps or early-stage colorectal tumors. About 230 patients scheduled for a colonoscopy or surgery will take either linaclotide or a placebo pill daily for one week before their procedure. Researchers will analyze tissue samples to see if the drug activates certain pathways that might be important for controlling cell growth.
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Contacts and locations
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Locations
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Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111, United States
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Sidney Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, Pennsylvania, 19126, United States
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VA Puget Sound Health Care Sysem
Seattle, Washington, 98108, United States
Conditions
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