New shot may ease itchy hives in teens

NCT ID NCT03437278

First seen Jan 17, 2026 · Last updated May 21, 2026 · Updated 25 times

Summary

This study tested a drug called ligelizumab in 49 teens aged 12 to 18 with chronic spontaneous urticaria (long-lasting hives with no clear trigger). The goal was to see if adding ligelizumab to standard antihistamines could reduce itching and welts better than a placebo. Participants received injections and tracked their symptoms weekly. The trial was completed and focused on safety and symptom improvement.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Rosario, Santa Fe Province, S2000BRH, Argentina

  • Novartis Investigative Site

    Bahía Blanca, B8000JRB, Argentina

  • Novartis Investigative Site

    Buenos Aires, C1125ABE, Argentina

  • Novartis Investigative Site

    Brussels, 1200, Belgium

  • Novartis Investigative Site

    Montreal, Quebec, H3H 1P3, Canada

  • Novartis Investigative Site

    Québec, Quebec, G1V 4W2, Canada

  • Novartis Investigative Site

    Berlin, 13353, Germany

  • Novartis Investigative Site

    Mainz, 55131, Germany

  • Novartis Investigative Site

    Budapest, HUN, 1037, Hungary

  • Novartis Investigative Site

    Nashik, Maharashtra, 422 101, India

  • Novartis Investigative Site

    New Delhi, National Capital Territory of Delhi, 110 060, India

  • Novartis Investigative Site

    Bikaner, Rajasthan, 334001, India

  • Novartis Investigative Site

    Saint Petersburg, 191015, Russia

  • Novartis Investigative Site

    Saint Petersburg, 191123, Russia

  • Novartis Investigative Site

    Smolensk, 214019, Russia

  • Novartis Investigative Site

    Barcelona, Barcelona, 08006, Spain

  • Novartis Investigative Site

    Esplugues de Llobregat, Barcelona, 08950, Spain

  • Novartis Investigative Site

    Taipei, Taiwan, 10002, Taiwan

  • Novartis Investigative Site

    Aydin, Turkey, 09100, Turkey (Türkiye)

  • Novartis Investigative Site

    Ankara, 06100, Turkey (Türkiye)

Conditions

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