Ultrasound zaps brain to unlock new treatments for addiction and pain

NCT ID NCT05147103

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study explores how different durations of low-intensity focused ultrasound (LIFU) can temporarily change brain activity in healthy adults. Participants undergo brain imaging and then receive ultrasound pulses while muscle responses are measured. The goal is to better understand how this noninvasive technique works, which may one day lead to treatments for addiction, pain, and mental health issues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Low-Intensity Focused Ultrasound (LIFU)
What this could lead to
If successful, this could help develop noninvasive brain stimulation treatments for addiction, pain, and mental health conditions.
What could go wrong
This is an early-stage study focused on basic brain responses, not a treatment trial. It may not lead to clinical applications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fralin Biomedical Research Institute

    Roanoke, Virginia, 24016, United States