Spinal fluid test could spot hidden lymphoma in the brain

NCT ID NCT06090162

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 38 times

Summary

This study is testing a new liquid biopsy that looks for tumor DNA in spinal fluid to see if it can better detect lymphoma that has spread to the brain or spinal cord. Researchers will compare this test to standard methods in 64 people newly diagnosed with high-risk B-cell lymphoma. If successful, this approach could help doctors identify who needs stronger treatment to prevent or manage central nervous system involvement.

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Contacts and locations

Locations

  • CHUV - Départment d'oncologie

    Lausanne, 1011, Switzerland

  • Hopitaux Universitaire de Genève (HUG)

    Geneva, 1205, Switzerland

  • Hôpital Fribourgeois - Hôpital Cantonal

    Fribourg, 1708, Switzerland

  • Hôpital du Valais, Hôpital de Sion

    Sion, 1951, Switzerland

  • Inselspital Bern - Universitätsklinik für Medizinische Onkologie

    Bern, 3010, Switzerland

  • Istituto Oncologico della Svizzera Italiana (IOSI)

    Bellinzona, 6500, Switzerland

  • Kantonspital Aarau

    Aarau, 5001, Switzerland

  • Kantonsspital Baselland

    Liestal, 4410, Switzerland

  • Kantonsspital Graubünden

    Chur, 7000, Switzerland

  • Kantonsspital Münsterlingen

    Münsterlingen, 8596, Switzerland

  • Kantonsspital St. Gallen

    Sankt Gallen, 9007, Switzerland

  • Klinik für Hämatologie und Onkologie Hirslanden Zürich

    Zurich, 8032, Switzerland

  • Stadtspital Triemli Zürich

    Zurich, 8063, Switzerland

  • Universitätsspital Basel

    Basel, 4056, Switzerland

Conditions

Explore the condition pages connected to this study.