New hope for kids with Tough-to-Treat leukemia

NCT ID NCT04240002

Summary

This study tested a new drug, gilteritinib, combined with standard chemotherapy in children and young adults with a specific, aggressive form of acute myeloid leukemia (AML) that had come back or did not respond to initial treatment. The goal was to find a safe and effective dose and see if the combination could put the cancer into remission. The trial was for patients aged 6 months to under 21 years old with a specific genetic marker (FLT3/ITD mutation) in their cancer cells.

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Contacts and locations

Locations

  • SIte IT39001

    Roma, 165, Italy

  • Site DE49004

    Essen, North Rhine-Westphalia, 45147, Germany

  • Site ES34001

    Barcelona, 08950, Spain

  • Site GB44001

    Birmingham, B4 6NH, United Kingdom

  • Site GB44005

    Cardiff, CF14 4XW, United Kingdom

  • Site UK44007

    Sutton, United Kingdom

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

Conditions

Explore the condition pages connected to this study.