New combo aims to shrink Hard-to-Treat colon tumors
NCT ID NCT06699836
First seen Oct 01, 2025 · Last updated May 16, 2026 · Updated 30 times
Summary
This study tests whether adding the experimental drug leronlimab to standard chemotherapy can shrink tumors in people with a common type of advanced colorectal cancer that has stopped responding to prior treatments. About 60 adults with microsatellite stable (MSS) metastatic colorectal cancer will receive either a low or high dose of leronlimab alongside standard drugs. The goal is to see if the combination improves tumor response and is safe.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope Orange County Lennar Foundation Cancer Center
RECRUITINGIrvine, California, 92618, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Fox Chase Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19111, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Georgetown University Medical Center
RECRUITINGWashington D.C., District of Columbia, 20007, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Norton Cancer Institute, Brownsboro Hospital Campus
RECRUITINGLouisville, Kentucky, 40241, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Pacific Hematology Oncology Associates
COMPLETEDSan Francisco, California, 94115, United States
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Summit Cancer Center
RECRUITINGSpokane, Washington, 99208, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68198, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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