Can a lenticule implant clear cloudy corneas from viral infection?
NCT ID NCT05123014
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This trial tests a two-part approach for people with corneal scarring caused by adenoviral keratitis. Surgeons first remove the scarred tissue using a laser technique called SMILE, then implant a fresh, clear corneal lenticule of the same size into the pocket. Patients also receive autologous serum eye drops to support healing. The goal is to see whether this can restore corneal transparency and improve vision without the scarring coming back.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a fresh corneal lenticule (stromal tissue) implanted in the eye plus autologous serum eye drops
- What this could lead to
- If it works, this approach could offer a new way to restore corneal transparency and improve vision in people with stubborn scarring from adenoviral keratitis.
- What could go wrong
- This is a small, early-stage trial with 45 participants. The procedure involves surgery and carries risks such as infection, graft rejection, or no lasting improvement in vision.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Eye Hospital Pristina
Pristina, 10000, Kosovo