New hope for kids with rare immune disease

NCT ID NCT05438407

Summary

This study is testing a medication called leniolisib in children aged 4 to 11 who have a rare genetic immune disorder called APDS. The main goals are to see if the drug is safe for children, how their bodies process it, and if it can help reduce swollen lymph nodes and infections. The trial has two parts: a 12-week initial study and a longer one-year follow-up to monitor safety over time.

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Contacts and locations

Locations

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30322, United States

  • Institute of Science Tokyo Hospital

    Tokyo, 113-8519, Japan

  • Kyoto University Hospital

    Kyoto, 606-8507, Japan

  • National Institutes of Health

    Bethesda, Maryland, 20814, United States

  • Necker Hospital Paris

    Paris, 75015, France

  • Stanford University

    Standford, California, 94305-5366, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.