Hope for tots with rare immune disease in new drug trial

NCT ID NCT05693129

Summary

This study is testing a drug called leniolisib in very young children (ages 1 to 6) who have a rare genetic immune disorder called APDS. The goal is to see if the drug is safe and effective at controlling the disease by reducing swollen lymph nodes and infections. The children will take the drug orally for a year to see how well it works over time.

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Contacts and locations

Locations

  • Great Ormond Street Hospital

    London, WC1N3JH, United Kingdom

  • Hospital Pediátrico de Coimbra da ULS Coimbra UNIDADE LOCAL DE SAÚDE DE COIMBRA

    Coimbra, 3000-075, Portugal

  • Hospital Universitario Virgen del Rocío

    Seville, 41013, Spain

  • Institute of Science Tokyo Hospital

    Tokyo, 113-8519, Japan

  • Kyoto University Hospital

    Kyoto, 606-8507, Japan

  • National Institutes of Health

    Bethesda, Maryland, 20814, United States

  • Rainbow Childrens Hospital

    Shaker Heights, Ohio, 44122, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.