MEN1 tumor drug trial halted after just 3 patients

NCT ID NCT05605587

First seen Nov 17, 2025 · Last updated Jun 12, 2026 · Updated 21 times

Summary

This study tested whether leflunomide, a drug already used for arthritis, could shrink or stabilize tumors in people with MEN1, a genetic condition that causes multiple tumors. Only 3 adults with a MEN1 gene mutation and at least one tumor joined before the trial was stopped early. The goal was to see if 6 months of daily leflunomide could control tumor growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Unispital Basel

    Basel, 4053, Switzerland

Conditions

Explore the condition pages connected to this study.