New cell therapy takes on Hard-to-Treat myeloma

NCT ID NCT07100067

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new cell therapy called LCAR-F33S in 35 people with multiple myeloma that has come back or stopped responding to other treatments. The therapy uses a patient's own immune cells, which are modified in a lab to attack the cancer. The main goals are to check safety, find the right dose, and see if it shrinks tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
LCAR-F33S cells (a type of CAR T-cell therapy made from the patient's own immune cells)
What this could lead to
If it works, this could offer a new treatment option for people with multiple myeloma that has stopped responding to standard therapies.
What could go wrong
This is a very early, small study (35 people) focused on safety and dosing. The treatment may not work, and there are risks of serious side effects like cytokine release syndrome.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Boren Hospital

    NOT_YET_RECRUITING

    Beijing, China

  • Institute of Hematology & Blood Diseases Hospital

    RECRUITING

    Tianjin, China

  • Institute of Hematology & Blood Diseases Hospital

    RECRUITING

    Tianjin, China

  • Wuhan Union Hospital

    RECRUITING

    Wuhan, China

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