New hope for hard-to-treat myeloma: experimental drug LBL-034 enters human trials
NCT ID NCT06049290
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug called LBL-034 in people whose multiple myeloma has returned or no longer responds to standard treatments. The trial has two phases: first, finding the safest dose, and then checking how well the drug shrinks tumors. About 342 adults will take part across multiple centers.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fujian Medical University Union Hospital
NOT_YET_RECRUITINGFuzhou, Fujian, 350000, China
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Henan Cancer Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, 450008, China
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Institute of hematology & blood diseases hospital, chinese academy of medical sciences & peking union medical college
NOT_YET_RECRUITINGTianjin, Tianjin Municipality, 300000, China
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Peking University People's Hospital
RECRUITINGBeijing, Beijing Municipality, 100044, China
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Peking University Shougang Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100144, China
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Qingdao Municipal Hospital
RECRUITINGQingdao, Shandong, 266011, China
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Shanghai Fourth People's Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200000, China
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Shanxi Bethune Hospital
RECRUITINGTaiyuan, Shanxi, 030000, China
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Shengjing Hospital of China Medical University
RECRUITINGShengyang, Liaoning, 117004, China
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Shenzhen Second People's Hospital
RECRUITINGShenzhen, Guangdong, 518035, China
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 516000, China
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The Afliliated Hospital of Guizhou Medical Univeristy
RECRUITINGGuiyang, Guizhou, 563000, China
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The First Affiliated Hospital Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310000, China
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The First Affiliated Hospital of Henan University
RECRUITINGLuoyang, Henan, 471003, China
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The First Affiliated Hospital of Ningbo University
RECRUITINGNingbo, Zhejiang, 315000, China
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The First Affiliated Hospital of Soochow University
NOT_YET_RECRUITINGSuzhou, Jiangsu, 215006, China
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The First Affiliated Hospital of Wannan Medical College
RECRUITINGWuhu, Anhui, 241001, China
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The First Affiliated Hospital of Wenzhou Medical University
RECRUITINGWenzhou, Zhejiang, 325000, China
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The First Affiliated Hospital of Xi'an Jiao Tong University
NOT_YET_RECRUITINGXi’an, Shanxi, 710061, China
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The First Affiliated Hospital of Xiamen University
RECRUITINGXiamen, Fujian, 361000, China
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The First Affiliated Hospital of Zhengzhou University
NOT_YET_RECRUITINGZhengzhou, Henan, 450052, China
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The First Bethune Hospital of Jilin University
RECRUITINGChangchun, Jilin, 130000, China
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The Second Affiliated Hospital of Hainan Medical University
RECRUITINGHaikou, Hainan, 570000, China
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The Second Affiliated Hospital of Xi'an Jiaotong University (Xibei Hospital)
RECRUITINGXi’an, Shanxi, 710004, China
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Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430000, China
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Xiangya Hospital of Central South University
NOT_YET_RECRUITINGChangsha, Hunan, 410008, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Engineered immune cells take aim at Hard-to-Treat myeloma
- Can engineered immune cells outsmart Treatment-Resistant myeloma?
- Can a lower dose of a myeloma drug keep the disease in check with fewer side effects?
- A pre-treatment pill may supercharge cancer-fighting immune cells
- New antibody combo aims to stall multiple Myeloma's return
- Real-World data may reveal best Second-Line therapy for multiple myeloma