New drug cocktail aims to shrink Hard-to-Treat neuroendocrine tumors

NCT ID NCT06157827

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new drug called LBL-024 combined with standard chemotherapy (etoposide plus platinum) as a first treatment for people with advanced neuroendocrine carcinoma. About 178 adults aged 18-75 will take part to see if the combination is safe and helps shrink tumors. The trial is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LBL-024 combined with etoposide and platinum chemotherapy

What this could lead to

If successful, this could offer a new first-line treatment option for advanced neuroendocrine carcinoma, potentially improving tumor shrinkage and delaying disease progression.

What could go wrong

This is an early-phase trial (Phase 1/2) with a small number of participants, so the benefits are uncertain. The combination may cause significant side effects, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neuroendocrine carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Anhui Cancer Hospital

    RECRUITING

    Hefei, Anhui, 230031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Anhui Provincial Hospital

    RECRUITING

    Hefei, Anhui, 230001, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing GoBroad Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100070, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chongqing University Cancer Hospital

    RECRUITING

    Chongqing, Chongqing Municipality, 400030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fujian Cancer Hospital

    RECRUITING

    Fuzhou, Fujian, 350014, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guangxi Medical University Cancer Hospital

    RECRUITING

    Nanning, Guangxi, 530021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Harbin Medical University Cancer Hospital

    RECRUITING

    Harbin, Heilongjiang, 150081, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henan Cancer Hospital

    RECRUITING

    Zhengzhou, Henan, 450008, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hubei Cancer Hospital

    RECRUITING

    Wuhan, Hubei, 430079, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Liaoning Cancer Hospital

    RECRUITING

    Shenyang, Liaoning, 110801, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Qilu Hospital of Shandong University

    RECRUITING

    Jinan, Shandong, 250063, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shandong Cancer Hospital

    RECRUITING

    Jinan, Shandong, 250117, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanxi Cancer hospital

    RECRUITING

    Taiyuan, Shanxi, 030013, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sir Run Run Shaw Hospital,Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310016, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun Yat-sen University Cancer Center (SYSUCC)

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310003, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Guangdong Pharmaceutical University

    RECRUITING

    Guangzhou, Guangdong, 510080, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Henan University of Science and Technology

    RECRUITING

    Luoyang, Henan, 471003, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital, Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310003, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital of Sichuan University

    RECRUITING

    Chengdu, Sichuan, 610044, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xiangyang Central Hospital

    RECRUITING

    Xiangyang, Hubei, 441000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••