New drug combo shows promise in shrinking Hard-to-Treat tumors

NCT ID NCT05516914

First seen Dec 10, 2025 · Last updated May 10, 2026 · Updated 20 times

Summary

This study tested a combination of two experimental drugs, LBL-007 and tislelizumab, in 98 adults with advanced solid tumors. The main goals were to find safe doses and see if the drugs could shrink tumors. The trial was completed and focused on safety and early signs of effectiveness.

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Contacts and locations

Locations

  • Anhui Cancer Hospital

    Hefei, Anhui, 230031, China

  • Fujian Cancer Hospital

    Fuzhou, Fujian, 350001, China

  • Guangxi Medical University Cancer Hospital

    Nanning, Guangxi, 530000, China

  • Hubei Cancer Hospital

    Wuhan, Hubei, 430000, China

  • Huizhou Municipal Central Hospital

    Huizhou, Guangdong, 516000, China

  • Hunan Cancer Hospital

    Changsha, Hunan, 410000, China

  • Jiangxi Cancer Hospital

    Nanchang, Jiangxi, 330029, China

  • Sun Yat-Sen Memorial Hospital,Sun Yat-Sen University

    Guangzhou, Guangdong, 510120, China

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

  • The First Affiliated Hospital of Guangxi Medical University

    Nanning, Guangxi, 530021, China

  • The First People's Hospital of Yu Lin

    Yulin, Guangxi, 537000, China

  • The Second Affiliated Hospital of Hainan Medical University

    Haikou, Hainan, 570000, China

  • Union Hospital Tongji Medical College Huazhong University of Science And Technology

    Wuhan, Hubei, 430022, China

  • West China Hospital of Sichuan University

    Chengdu, Sichuan, 610041, China

  • Zhejiang Cancer Hospital

    Hangzhou, Hangzhou, 310000, China

Conditions

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