New drug targets Hard-to-Treat tumors in early trial

NCT ID NCT05707676

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 23 times

Summary

This early-phase study tested a new drug called LB4330 in 40 people with advanced solid tumors that had stopped responding to standard treatments. The drug is designed to help the immune system attack cancer cells by targeting a protein called Claudin 18.2. The main goals were to check safety, find the right dose, and see how the body processes the drug.

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Contacts and locations

Locations

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200120, China

Conditions

Explore the condition pages connected to this study.