New Dual-Action antibody enters early human trials for tough cancers

NCT ID NCT05357651

First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 27 times

Summary

This early-stage study is testing an experimental drug called LB1410 in people with advanced solid tumors or lymphoma that hasn't responded to standard treatments. The drug is a bispecific antibody designed to block two proteins (PD-1 and TIM-3) that can help cancer hide from the immune system. The main goals are to check if the drug is safe, what side effects it causes, and how the body processes it. About 100 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Pulmonary Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.