Could a laxative before colon surgery make the operation easier?
NCT ID NCT07820696
First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time
Summary
Researchers are testing whether giving an oral laxative before elective laparoscopic colorectal surgery changes the size of the small bowel and how hard the operation is to perform. Sixty adults scheduled for this surgery join one of two groups: oral laxative plus a rectal enema, or a rectal enema alone. During surgery, the team measures the diameter of the jejunum and ileum and tracks difficulty, operating time, complications, and early recovery. The goal is to learn whether the laxative affects conditions during surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- an oral laxative given as part of bowel preparation before surgery
- What this could lead to
- If it helps, this could give surgeons a simple way to make laparoscopic colorectal operations easier and possibly safer.
- What could go wrong
- This is a small pilot study of 60 people, so any difference may be too slight to matter or may not hold in larger groups. Laxatives can cause dehydration, cramping, and electrolyte shifts before surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Scheduled for elective laparoscopic colorectal resection * American Society of Anesthesiologists (ASA) physical status I-III * Able and willing to provide written informed consent Exclusion Criteria: * Requirement for emergency surgery * Mechanical intestinal obstruction, gastrointestinal perforation, or generalized peritonitis * Anticipated extensive intra-abdominal adhesions * Active inflammatory bowel disease * Pregnancy * Serious systemic disease constituting a contraindication to oral laxative use * Inability to perform standardized intraoperative small-bowel diameter measurements
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Health Sciences Türkiye, Van Training and Research Hospital
RECRUITINGVan, Van, 65300, Turkey (Türkiye)
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