Laser combo may cut eye injection burden for vein blockage patients

NCT ID NCT04444492

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether adding targeted laser treatment to the standard ranibizumab injections can help people with macular edema (swelling) from a central retinal vein occlusion need fewer injections over time. About 88 adults with this condition will receive either injections alone or injections plus laser. The goal is to see if the combination leads to a longer treatment-free period and fewer total injections.

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Conditions

The condition(s) this trial relates to.

central retinal vein occlusion with macular edema retinal vein occlusion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Augen-OP-Zentrum Zschopau, Praxis für Augenheilkunde

    Zschopau, Germany

  • Augenzentrum am St. Franziskus-Hospital Münster

    Münster, 48145, Germany

  • Hannover MHH Universitätsklinik für Augenheilkunde

    Hanover, 30625, Germany

  • Klinikum der Stadt Ludwigshafen Augenklinik

    Ludwigshafen, 67063, Germany

  • Ludwig-Maximilians-Universität München, Augenklinik

    München, Germany

  • Medizinische Universität Innsbruck, Klinik für Augenheilkunde und Optometrie

    Innsbruck, 6020, Austria

  • University Hospital of Leipzig Department of Ophthalmology

    Leipzig, 04103, Germany

  • Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg Klinik für Augenheilkunde

    Marburg, 35043, Germany

  • Universitätsklinikum Gießen, Klinik und Poliklinik für Augenheilkunde

    Giessen, Germany

  • Universitätsklinikum Klinik für Augenheilkunde Freiburg

    Freiburg im Breisgau, 79106, Germany

  • Universitätsklinikum Tübingen, Department für Augenheilkunde

    Tübingen, Germany

  • Universitätsklinikum Ulm, Klinik für Augenheilkunde

    Ulm, Germany