Voice-Saving cancer trial: which chemo regimen works best?
NCT ID NCT03340896
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 24 times
Summary
This phase 3 trial tests two chemotherapy strategies to preserve larynx function in 256 patients with advanced larynx or hypopharynx cancer. One group gets induction chemo (TPF) followed by radiation; the other gets radiation with cisplatin. The main goal is to see which approach better avoids death, total laryngectomy, or tracheotomy within 2 years.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Centre Jean Bernard
Le Mans, 72000, France
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