New drug combo aims to spare voice box in advanced throat cancer

NCT ID NCT07423078

First seen Feb 27, 2026 · Last updated May 13, 2026 · Updated 11 times

Summary

This study tests whether adding the immunotherapy drug toripalimab to standard chemotherapy can help control advanced laryngeal or hypopharyngeal cancer while avoiding removal of the voice box (laryngectomy). About 87 adults with stage III-IV disease that is surgically removable will receive the combination. The main goal is to see how many patients remain cancer-free after one year.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Hillman Cancer

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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