Experimental gene therapy aims to save sight in rare eye disease

NCT ID NCT07174726

First seen Nov 01, 2025 · Last updated May 26, 2026 · Updated 31 times

Summary

This study tests a gene therapy called laruparetigene zovaparvovec (AGTC-501) given in both eyes to 10 males aged 12–50 with X-linked retinitis pigmentosa, a genetic condition that causes vision loss. The main goal is to check safety and see if the treatment can preserve or improve eyesight. Participants will be followed for at least a year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bascom Palmer Eye Institute

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cincinnati Eye Institute

    RECRUITING

    Cincinnati, Ohio, 45242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Duke Eye Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-••••

    Contact

  • OHSU Casey Eye Institute

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Retina Foundation of the Southwest

    RECRUITING

    Dallas, Texas, 75231, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Florida Jacksonville Ophthalmology

    RECRUITING

    Jacksonville, Florida, 32209, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.