New hope for kids with rare, deadly brain cancer?

NCT ID NCT04655404

Summary

This early-stage study is testing a drug called larotrectinib in children and young adults (up to age 21) newly diagnosed with aggressive brain tumors that have a specific genetic feature called an NTRK fusion. The main goals are to see if the drug can control the tumor and to check its safety when given alone or with standard treatments like chemotherapy or radiation. The study will enroll about 15 participants.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    WITHDRAWN

    Chicago, Illinois, 60611, United States

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's National Medical Center

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Health System

    RECRUITING

    Durham, North Carolina, 27708, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopp Children's Cancer Center at NCT Heidelberg (KiTZ)

    RECRUITING

    Heidelberg, Baden-Wurttemberg, 69120, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montreal Children's Hospital

    RECRUITING

    Montreal, Quebec, H4A3J1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Perth Children's Hospital

    RECRUITING

    Perth, Western Australia, 6000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Queensland Children's Hospital

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Starship Children's Hospital

    RECRUITING

    Auckland, Grafton, 1023, New Zealand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sydney Children's Hospital

    RECRUITING

    Randwick, New South Wales, 2031, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Hospital for Sick Children (SickKids)

    RECRUITING

    Toronto, Ontario, M5G1X8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Berlin

    RECRUITING

    Berlin, Germany

    Contact Email: •••••@•••••

  • University Hospital Koln

    RECRUITING

    Cologne, Germany

    Contact Email: •••••@•••••

  • University Medical Center Augsburg

    RECRUITING

    Augsburg, Germany

    Contact Email: •••••@•••••

  • University Medical Center Gottingen

    RECRUITING

    Göttingen, Germany

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.