Could an old HIV drug help fight cancer?

NCT ID NCT06494579

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding lamivudine, an HIV drug, to standard immunotherapy can help shrink or control advanced solid tumors that have stopped responding to treatment. About 12 to 24 adults with various solid cancers will receive lamivudine alongside their current immunotherapy. The goal is to see if this combination is safe and can slow tumor growth.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States