New pill shows promise for Hard-to-Treat blood cancer

NCT ID NCT07609823

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests lacutoclax, a daily pill that blocks a protein helping cancer cells survive, in 75 adults with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma. Participants take the drug until their disease worsens or side effects become too severe. The main goal is to see how many people's cancer shrinks or disappears.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lacutoclax (a BCL-2 inhibitor drug taken as a daily pill)

What this could lead to

If successful, this could provide a new treatment option for people with CLL/SLL whose cancer has returned or stopped responding to prior therapies.

What could go wrong

This is an early-phase, single-arm study with no placebo group, so results are preliminary. The drug may not work for everyone and could cause side effects like low blood counts or infections.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia chronic lymphocytic leukemia/small lymphocytic lymphoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••