New pill shows promise for Hard-to-Treat blood cancer
NCT ID NCT07609823
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times
Summary
This phase 2 trial tests lacutoclax, a daily pill that blocks a protein helping cancer cells survive, in 75 adults with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma. Participants take the drug until their disease worsens or side effects become too severe. The main goal is to see how many people's cancer shrinks or disappears.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lacutoclax (a BCL-2 inhibitor drug taken as a daily pill)
- What this could lead to
- If successful, this could provide a new treatment option for people with CLL/SLL whose cancer has returned or stopped responding to prior therapies.
- What could go wrong
- This is an early-phase, single-arm study with no placebo group, so results are preliminary. The drug may not work for everyone and could cause side effects like low blood counts or infections.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The First Affiliated Hospital of Nanjing Medical University
RECRUITINGNanjing, Jiangsu, China