New shot therapy targets hard-to-treat skin cancer in phase 2 trial

NCT ID NCT07228442

First seen Nov 15, 2025 · Last updated May 07, 2026 · Updated 21 times

Summary

This study tests a new treatment for people with advanced skin cancer (squamous cell carcinoma) that has stopped responding to or cannot tolerate standard immunotherapy. The treatment is a combination of two drugs (L19IL2 and L19TNF) injected directly into the tumors once a week for up to 4 weeks, with a possible second course. The goal is to see if this approach can shrink tumors and control the disease. About 92 participants will be enrolled.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LOCALLY ADVANCED CUTANEOUS SQUAMOUS CELL CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

    Contact

  • Winship Cancer Institute, Emory University

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.