Experimental immune therapy tested for Tough-to-Treat blood cancer
NCT ID NCT04880434
Summary
This study tested an experimental treatment called KTE-X19, a type of CAR T-cell therapy, for adults with mantle cell lymphoma that has returned or stopped responding to other treatments. The treatment involves collecting and genetically modifying a patient's own immune cells to fight the cancer. The main goal was to see how well the therapy worked and how long the responses lasted in patients who had not received a specific type of prior drug.
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Contacts and locations
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Locations
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Academisch Medisch Centrum
Amsterdam, 1100, Netherlands
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Advocate Aurora Health - Advocate Lutheran General Hospital
Park Ridge, Illinois, 60068, United States
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Banner MD Anderson Cancer Center
Gilbert, Arizona, 85234, United States
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Baylor Cancer Hospital
Dallas, Texas, 75246, United States
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CHU de Montpellier
Montpellier, 34295, France
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CHU de Rennes
Rennes, 35033, France
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Centre Hospitalier Lyon Sud
Pierre-Bénite, 69495, France
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Cleveland Clinic - Taussig Cancer Institute
Cleveland, Ohio, 44195, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Duke University
Durham, North Carolina, 27710, United States
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Emory University
Atlanta, Georgia, 30322, United States
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Erasmus MC
Rotterdam, 3015 CE, Netherlands
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Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111, United States
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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Hopital Haut-Leveque
Pessac, 44035, France
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Hospital Clinic Barcelona
Barcelona, Spain
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Hospital Saint Louis
Paris, 75010, France
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Hospital Universitari Vall D'Hebron
Barcelona, 08035, Spain
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Hospital Universitario de Salamanca
Salamanca, 37007, Spain
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Johannes Gutenberg University Hospital-University Mainz
Mainz, 55101, Germany
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Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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Kings College Hospital
London, SE5 9RS, United Kingdom
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Loyola University Medical Center
Maywood, Illinois, 60153, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Manchester Royal Infirmary
Manchester, M13 9WL, United Kingdom
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Munich University of Technology-Medical Faculty- Ethics Committee
München, 81377, Germany
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Ohio State University
Columbus, Ohio, 43220, United States
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Queen Elizabeth University Hospital
Glasgow, G51 4TF, United Kingdom
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Sarah Cannon - Tenessee
Nashville, Tennessee, 37203, United States
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Sarah Cannon- Denver
Denver, Colorado, 80218, United States
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Stanford University
Palo Alto, California, 94305, United States
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Swedish Cancer Institute
Seattle, Washington, 98104, United States
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Universitaetsklinikum Wuerzburg
Würzburg, 97080, Germany
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University California Los Angeles (UCLA)
Santa Monica, California, 90404, United States
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University Medical Center Groningen
Groningen, 9700 RB, Netherlands
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Miami
Miami, Florida, 33136, United States
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University of Rochester
Rochester, New York, 14642, United States
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Vanderbilt University
Nashville, Tennessee, 37232, United States
Conditions
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