New cell therapy shows promise for kids with relapsed blood cancers

NCT ID NCT02625480

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 23 times

Summary

This study tested a treatment called KTE-X19 in 95 children and teens whose leukemia or lymphoma had returned or stopped responding to standard therapy. The treatment uses the patient's own immune cells, modified to better attack cancer cells. The goal was to see if it is safe and can shrink or eliminate the cancer, but it is not a cure—patients may still need ongoing care.

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Contacts and locations

Locations

  • Ann & Robert H. Lurie Children's Hospital

    Chicago, Illinois, 60611, United States

  • Bambino Gesù Children's Hospital

    Rome, 00165, Italy

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Orange County

    Orange, California, 92868, United States

  • Children's Hospitals and Clinics of Minnesota

    Minneapolis, Minnesota, 55404, United States

  • Columbia University Irving Medical Center/Morgan Stanley Children's Hospital-NYP

    New York, New York, 10032, United States

  • Hopital Robert Debre - Sevice d'Hemato-immunologic

    Paris, 75935, France

  • Hopital d'Enfants la Timone

    Marseille, 13385, France

  • Hospital Sant Joan de Déu

    Barcelona, 08950, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Institut d'Hematologie et Oncologie Pediatrique

    Lyon, 69373, France

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • Jurasz University Hospital 1; Collegium Medicum

    Bydgoszcz, 85-094, Poland

  • Kapi'olani Medical Center for Women and Children

    Honolulu, Hawaii, 96826, United States

  • Karolinska University Hospital

    Stockholm, SE-141 86, Sweden

  • Monroe-Carell Jr. Children's Hospital at Vanderbilt

    Nashville, Tennessee, 37232, United States

  • Prinses Maxima Centrum

    Utrecht, 3508, Netherlands

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • The Hospital for Sick Children

    Toronto, M5G 1X8, Canada

  • The University of Texas M.D. Anderson Cancer Center

    Houston, Texas, 77030, United States

  • UCSF Benioff Children's Hospital

    San Francisco, California, 94158, United States

  • Unité d'Oncologie et Hématologie Pédiatriques

    Bordeaux, 33 000, France

  • University Hospital Brno

    Brno, 625 00, Czechia

  • University Hospital Gent

    Ghent, 9000, Belgium

  • University Medical Center Hamburg-Eppendorf (UKE)

    Hamburg, 20246, Germany

  • University of Miami Hospital & Clinics

    Miami, Florida, 33136, United States

  • University of Rochester Medical Center

    Rochester, New York, 14642, United States

  • University of Virginia Health System, Pediatric Hematology/Oncology Clinic

    Charlottesville, Virginia, 22908, United States

  • Wroclaw Medical University

    Wroclaw, 50-556, Poland

Conditions

Explore the condition pages connected to this study.